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Pharma Investments, Ventures & Law Weekly

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Acute Promyelocytic Leukemia



Research on acute promyelocytic leukemia published by A. Kohno et al



April 27th, 2008

"Acute promyelocytic leukemia (APL) is the most curable subtype of acute myeloid leukemia. Second complete remission (CR2) can be easily achieved with several therapeutic options even after relapse," scientists in Japan report.

"However, the optimal strategy to treat APL in CR2 is still controversial. We retrospectively compared the outcome of autologous (auto) and allogeneic (allo) hematopoietic stem cell transplantation (HSCT) for patients with APL in CR2 or CR3. Fifteen patients received auto and 13 received allo HSCT between 1999 and 2004 at eight hospitals belonging to the Nagoya Blood and Marrow Transplantation Group. Four-year disease-free survival (DFS) and...


Source: Pharma Investments, Ventures & Law Weekly (2008-04-27)

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