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Adverse Drug Reactions
New findings in adverse drug reactions described by L.Y. Carreon and co-researchers
April 27th, 2008
"Case series from a single spine specialty clinic. This study analyzed wound related or anaphylactic adverse events in patients re-exposed to rhBMP-2," scientists writing in the journal Spine report. "The use of recombinant bone morphogenetic protein (rhBMP-2) as a bone graft substitute is increasing. There is concern that re-exposing patients to rhBMP-2, might result in a hyper-inflammatory response causing wound problems or an allergic reaction. Ninety-six patients who had at least 2 spine surgeries using rhBMP-2 (Infuse, Medtronic Sofamor Danek, Memphis, TN) were identified. Anteroposterior surgeries, surgeries for infection and trauma were excluded....
Source: Pharma Investments, Ventures & Law Weekly (2008-04-27)
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