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Acidosis Cell Biology
Study results from University Hospital provide new insights into acidosis cell biology
April 27th, 2008
A new study, 'Effect of acidic reperfusion on prolongation of intracellular acidosis and myocardial salvage,' is now available. "It has been proposed that intracellular acidosis may be the basis of the cardioprotection of different interventions, including postconditioning. However, contradictory reports exist on the effects of acidic reperfusion on myocardial salvage," investigators in Barcelona, Spain report. "Here we characterized the effect of lowering the pH of the reperfusion media (pHo) on intracellular pH (pHi) and cell death. The effect of acidic perfusion on reperfusion injury was studied in isolated rat hearts submitted to 40 min of ischaemia and 30 min of...
Source: Pharma Investments, Ventures & Law Weekly (2008-04-27)
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