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Pharma Investments, Ventures & Law Weekly

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Acute Myeloid Leukemia Therapy



Studies from University of Bari provide new data on acute myeloid leukemia therapy



May 4th, 2008

Current study results from the report, 'Similar mechanisms formed ring markers containing chromosome 12 pericentromeric region in two patients with therapy-related acute myeloid leukemia,' have been published. According to a study from Bari, Italy, "Two cases of therapy-related acute myeloid leukemia showed complex karyotypes, including a small ring and a larger D-chromosome. Multicolor fluorescence in situ hybridization and bacterial artificial chromosome and fosmid clones showed that both ring chromosomes were composed entirely of material excised from chromosome 12."

"The deleted segment of 12 was found fused to the short arm of a D-group chromosome. We hypothesized...


Source: Pharma Investments, Ventures & Law Weekly (2008-05-04)

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