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Pharma Investments, Ventures & Law Weekly

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Alcoholism



New research on alcoholism from Queen's University summarized



May 11th, 2008

"Although acetaminophen overdose is a leading cause of fulminant hepatic failure, it is controversial whether therapeutic doses of acetaminophen can cause hepatotoxicity in alcoholics, especially those rendered most vulnerable by recent abstinence. We performed a randomized, triple-blind, parallel-group trial comparing sustained-release acetaminophen, 1300mg orally q8h for 11 doses, against placebo," researchers in Kingston, Canada report.

"We enrolled chronic alcohol abusers (defined as >= 6 drinks daily for >= 6 weeks) who had discontinued alcohol consumption 12 to 72 hours prior to enrolment. Individuals with self-reported viral hepatitis, HIV or intravenous...


Source: Pharma Investments, Ventures & Law Weekly (2008-05-11)

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