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Pharma Investments, Ventures & Law Weekly

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Acid Reflux Disease



Data on acid reflux disease reported by researchers at University of Helsinki



May 11th, 2008

According to a study from Helsinki, Finland, "Oxidative stress has a role in the pathogenesis of gastroesophageal reflux disease (GERD). To investigate the redox balance in proximal esophagus before and 6 and 48 months after antireflux surgery."

"In 20 GERD patients and 9 controls oxidative stress by myeloperoxidase activity (MPO activity) and antioxidative capacity of esophageal mucosa by superoxide dismutase activity (SOD), and glutathione content (GSH) was measured from proximal esophageal samples. In proximal esophagus of GERD patients compared to controls', antioxidative capacity appearing as GSH level was significantly decreased (P < 0.001) at all time points...


Source: Pharma Investments, Ventures & Law Weekly (2008-05-11)

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