Pharma Investments, Ventures & Law Weekly
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Allergies
Research from R. Baker and co-researchers in the area of allergies described
May 11th, 2008
According to recent research from the United States, "Altered basophil degranulation phenotypes are found in patients with chronic idiopathic urticaria (CIU). To evaluate CIU disease severity in relation to basophil histamine release (HR) characteristics." "Patients with CIU were recruited from allergy and dermatology clinics. Patients with recent use of systemic corticosteroids or immunosuppressants were excluded. Patients completed disease severity surveys and had blood basophils isolated and stimulated for HR using polyclonal goat anti-human IgE and N-formyl-met-leu-plie. The HR was measured using automated fluorometry. Multivariate linear regression analyses were...
Source: Pharma Investments, Ventures & Law Weekly (2008-05-11)
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