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Pharma Investments, Ventures & Law Weekly

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Acid Reflux Disease Risk Factors



Research from Belfast City Hospital, Division of Gastroenterology provide new insights into acid reflux disease risk factors



May 11th, 2008

A report, 'No association between hOGG1, XRCC1, and XPD polymorphisms and risk of reflux esophagitis, Barrett's esophagus, or esophageal adenocarcinoma: results from the factors influencing the Barrett's adenocarcinoma relationship case-control study,' is newly published data in Cancer Epidemiology, Biomarkers & Prevention. According to recent research from Northern Ireland UK, "Reflux of gastric contents can lead to development of reflux esophagitis and Barrett's esophagus. Barrett's esophagus is a risk factor for esophageal adenocarcinoma."

"Damage to DNA may lead to carcinogenesis but is repaired through activation of pathways involving polymorphic enzymes,...


Source: Pharma Investments, Ventures & Law Weekly (2008-05-11)

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