Pharma Investments, Ventures & Law Weekly
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Adverse Drug Reactions
Study results from Princess Margaret Hospital broaden understanding of adverse drug reactions
May 18th, 2008
" A tool that quantifies the risk of treatment-related toxicity based on individual patient characteristics can augment the informed consent process and safety monitoring in the setting of phase II cancer treatment trials of molecularly targeted agents (MTAs). A regression model was constructed to predict the risk of a serious adverse event (SAE) with an MTA and presented as a nomogram," researchers in Toronto, Canada report. "Estimation of risk can be performed by integrating risk estimates from the nomogram and from a reference or average patient. Internal validation was performed using bootstrapping techniques. A total of 578 patients were treated with one of 14...
Source: Pharma Investments, Ventures & Law Weekly (2008-05-18)
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