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Pharma Investments, Ventures & Law Weekly

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Amnesia



New amnesia study findings have been reported by scientists at University of Washington, Medical Department



May 18th, 2008

"A middle-aged woman began experiencing spells of profound anterograde amnesia several months after beginning intrathecal baclofen treatment for generalized dystonia. Her spells met criteria for transient global amnesia, but were unusual because of their frequent recurrence and because their frequency was somewhat dose-dependent on baclofen," scientists writing in the journal Anesthesia and Analgesia report.

"Fludrocortisone decreased the frequency of these episodes, and sublingual nitroglycerin both prevented and terminated them. Baclofen-induced amnesia in rodents is a reliable model of memory impairment. In contrast, baclofen-induced memory impairment in...


Source: Pharma Investments, Ventures & Law Weekly (2008-05-18)

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