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Amyotrophic Lateral Sclerosis
Findings from University of Pisa advance knowledge in amyotrophic lateral sclerosis
May 18th, 2008
According to a study from Pisa, Italy, "ALS is a devastating neurodegenerative disorder with no effective treatment. In the present study, we found that daily doses of lithium, leading to plasma levels ranging from 0.4 to 0.8 mEq/liter, delay disease progression in human patients affected by ALS." "None of the patients treated with lithium died during the 15 months of the follow-up, and disease progression was markedly attenuated when compared with age-, disease duration-, and sex-matched control patients treated with riluzole for the same amount of time. In a parallel study on a genetic ALS animal model, the G93A mouse, we found a marked neuroprotection by lithium,...
Source: Pharma Investments, Ventures & Law Weekly (2008-05-18)
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