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Pharma Investments, Ventures & Law Weekly

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Actinomycosis



Researchers' work from University of Iowa focuses on actinomycosis



May 18th, 2008

"Cathelicidins are antimicrobial peptides found in epithelial and mucosal tissues as well as the secondary granules of neutrophils. SMAP29, a sheep cathelicidin, has differential antimicrobial properties against various pathogens, including periodontal organisms," scientists in the United States report.

"The purpose of this study was to evaluate the antimicrobial properties and cytotoxicity of SMAP29, SMAP28, and three congeners (SMAP18A, SMAP18D, and SMAP14A). The peptides at concentrations ranging from 0.25 to 250 mu g/ml were tested for their activity against multiple strains of Streptococcus mutans, Streptococcus sanguis, Actinomyces israelii, Actinomyces...


Source: Pharma Investments, Ventures & Law Weekly (2008-05-18)

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