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Anesthesia
Findings from H.A. Mowafi and co-researchers advance knowledge in anesthesia
May 18th, 2008
According to a study from Al Khobar, Saudi Arabia, "We hypothesized that pretreatment with IV granisetron would affect the sensory and motor components of spinal blockade through 5-HT3 receptor blockade. Forty unpremedicated patients scheduled for elective knee arthroscopy under spinal anesthesia were randomly allocated to receive either IV granisetron 1 mg (granisetron group) or saline (control group) on arrival to the operating room." "Two and half milliliters (12.5 mg) of hyperbaric bupivacaine 0.5% was injected intrathecally. Regression of the sensory level and motor blockade, and the hemodynamic changes were evaluated. There were no significant differences between...
Source: Pharma Investments, Ventures & Law Weekly (2008-05-18)
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