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Anesthesia
Research from M.G. Sommers and co-authors reveals new findings on anesthesia
May 18th, 2008
"Although our understanding of nociceptive processing during anesthesia has increased greatly over the last decade, many patients still experience hyperalgesia and acute pain postoperatively. The noxious-induced withdrawal reflex (NTWR) model is specifically designed and validated to quantitatively study the reaction on painful, multimodal stimuli in animals under anesthetic conditions," researchers in Netherlands report. "Since the anesthetic mechanisms differ between inhaled anesthetics and opioids, we evaluated the differential effects of isoflurane and fentanyl on c-fos expression at the lumbar level as a measure of nociceptive information transfer during general...
Source: Pharma Investments, Ventures & Law Weekly (2008-05-18)
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