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Pharma Investments, Ventures & Law Weekly

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Anesthesia



Research on anesthesia described by scientists at Wuhan University



May 18th, 2008

"Droperidol has a central antiemetic action and is widely used in the fields of psychiatry, anesthesia, and emergency medicine. It has been associated with prolongation of the QT inter-vat of the electrocardiogram, and it may also be associated with torsades de pointes and sudden death," researchers in Wuhan, People's Republic of China report.

"Although QT prolongation is consistent with droperidol-induced increases in cardiac ventricular action potential duration, the cellular mechanism for these observations has not been clearly studied. The rapidly activating delayed rectifier potassium channel, IKr, is a primary site of action of drugs causing QT prolongation and is...


Source: Pharma Investments, Ventures & Law Weekly (2008-05-18)

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