Pharma Investments, Ventures & Law Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Pharma Investments, Ventures & Law Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Acute Hepatitis
Research conducted at University of Messina has updated our knowledge about acute hepatitis
January 18th, 2009
According to a study from Messina, Italy, "Reactive oxygen species (ROC) are the main causes of carbon tetrachloride (CCl4)-induced acute liver injury. Chondroitin-4-sulphate(C4S) is known to inhibit lipid peroxidation through antioxidant mechanisms." "Activation of nuclear factor (NF)-kappa B and caspases may strongly intensify inflammation and cell damage, in addition to that directly exerted by ROS. We investigated whether treatment with C4S, besides exerting antioxidant activity, was able to modulate NF-kappa B and apoptosis activation in CCl4-induced liver injury in mice. Experimental approach: Acute hepatitis was induced in mice by an i.p. injection of CCl4....
Source: Pharma Investments, Ventures & Law Weekly (2009-01-18)
|
