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Aging
Research data from K.A. Baskerville and colleagues update understanding of aging
January 18th, 2009
According to a study from the United States, "The basal forebrain (BF) cholinergic system is selectively Vulnerable in human brain diseases, while the cholinergic groups ill the tipper pons of the brainstem (BS) resist neurodegeneration. Cholinergic neurons (200 per region per animal) were laser-microdissected from five young (8 months) and live aged (24 months) F344 rats from the BF and the BS pontine lateral dorsal tegmental/peduncuopontine nuclei (LDTN/PPN) and their expression profiles were obtained." "The bioinformatics program SigPathway was used to identify gene groups and pathways that were selectively affected by aging. In the BF cholinergic system, aging most...
Source: Pharma Investments, Ventures & Law Weekly (2009-01-18)
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