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Pharma Investments, Ventures & Law Weekly

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Aging



Research reports from Ohio State University provide new insights into aging



January 18th, 2009

According to a study from the United States, "The number of activated microglia increase during normal aging. stimulation of endocannabinoid receptors can reduce the number of activated microglia, particularly in the hippocampus, of young rats infused chronically with lipopolysaccharide (LPS). In the current study we demonstrate that endocannabinoid receptor stimulation by administration of WIN-55212-2 (2 mg/kg day) can reduce the number of activated microglia in hippocampus of aged rats and attenuate the spatial memory impairment in the water pool task."

"Our results suggest that the action of WIN-55212-2 does not depend upon a direct effect upon microgolia or...


Source: Pharma Investments, Ventures & Law Weekly (2009-01-18)

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