Coagulation

Reports from A.G.G. Turpie et al highlight recent research in coagulation

Published in Pharma Investments, Ventures and Law Weekly, August 9th, 2009

"Long-available anticoagulants including unfractionated and low-molecular-weight heparins (UFH and LMWHs, respectively) and vitamin K antagonists (VKAs), as well as the more recently introduced synthetic pentasaccharide, fondaparinux, have demonstrated efficacy in preventing thromboembolic events. However, all of them have a number of practical limitations," researchers in Hamilton, Canada report.

"UFH, LMWHs, and fondaparinux must be administered parenterally, making them less attractive for long-term prophylaxis, and heparins are associated with immune-mediated thrombocytopenia. Until recently, VKAs such as warfarin were the only approved oral anticoagulants, but they...

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Source: Pharma Investments, Ventures and Law Weekly (2009-08-09)

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