Adverse Drug Reactions

Researchers from Northwestern University, Division of Rheumatology detail new studies and findings in the area of adverse drug reactions

Published in Pharma Investments, Ventures and Law Weekly, October 25th, 2009

Fresh data on adverse drug reactions are presented in the report 'Intracellular signal pathways: potential for therapies.' "Drawbacks to current therapies for rheumatoid arthritis and the high cost of many of these drugs have lead to the investigation of novel approaches for treatment of this disease. One such tactic is the targeting of proteins involved in intracellular signal transduction," researchers in the United States report.

"Inhibitors of p38 kinase have largely failed in clinical trials, due to both lack of efficacy and adverse events. The degree of adverse events may reflect off-target effects or, conversely, may be a mechanism-related event subsequent to...

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Source: Pharma Investments, Ventures and Law Weekly (2009-10-25)

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