Life Sciences

Study findings from H.G. Sun et al broaden understanding of life sciences

Published in Pharma Investments, Ventures and Law Weekly, November 15th, 2009

According to recent research from Nanjing, People's Republic of China, "Bacillus subtilis fmbR-1 was obtained from wild-type B. subtilis fmbR by replacement of the native promoter of the surfactin operon with the inducible promoter Pspac. The recombinant B. subtilis fmbR-1 produced more antibacterial substances than the wild-type strain."

"The overproducing phenotype was related to the enhancement of antagonistic activities against Bacillus cereus. HPLC peaks of surfactin for recombinant fmbR-1 showed patterns of lipopeptides similar to those of the wild-type strain, and surfactin production of the recombinant fmbR-1 was up to about fivefold greater than that of the...

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Source: Pharma Investments, Ventures and Law Weekly (2009-11-15)

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