Pharma Law Weekly

NAS RA - Polypeptide protects brain neurons in aluminum neurotoxicosis

National Hyogo-Chuo Hospital - Spinal and bulbar muscular atrophy linked to myotonic dystrophy type 1

National Stroke Association - MATCH trial results: Adding aspirin to clopidogrel does not reduce stroke risk

National Yang Ming University - PhaQ regulates phasin expression in Bacillus megaterium

Naturally Vitamins - USP seal intented to help consumers locate quality supplements

Natus Medical, Inc. - Neonatal products company names two board members

Northwestern University - Restoration of NK cell development requires Fyn during early NK T cell ontogeny

Nuclear Medicine - Nuclear medicine patients warned of possible transportation checkpoint delays

OraSure Technologies, Inc. - Medical device manufacturer appoints new president and chief executive officer

Orthovita, Inc. - Marketing agreement announced for Vitagel and Cellpaker system

Osaka University - T-cell CD154 expression reduced in autoimmune thyroid disease

Oscient Pharmaceuticals Corporation - Enrollment completed for phase II trial of Ramoplanin for CDAD

Osman Gazi Mah, Erzurum - Plasma homocysteine level correlates with coronary artery disease

PTC Therapeutics, Inc. - Drug discovery company closes $50M Series E private placement financing

Pasteur Institute Iran - Type I signal peptidase from Leishmania is a target of the immune response

Peking University - Wild-type p16(INK4a) contains the proliferation of MCF-7 breast cancer cells

Penwest Pharmaceuticals Co. - Pharmaceutical company appoints senior VP, research and development

Peter MacCallum Cancer Inst., Melbourne - Some aspects of managing brain metastases remain controversial

Polio Vaccinations - Islamic state in Nigeria resumes polio vaccinations

Prescription Drugs - Biotech developing hard-to-abuse version of painkiller Oxycontin

RegeneRx Biopharmaceuticals, Inc. - Biopharmaceutical company elects directors at annual stockholders' meeting

Ricarimpex SAS - FDA approves leeches as medical devices

Royal Prince Alfred Hospital - N-terminal proCNP may be a marker for preeclampsia

San Raffaele Telethon Institute for Gene Therapy - Genetically modified stem cells reverse neurodegenerative symptoms in mice

Sanofi-Synthelabo - Agreement signed on the divestment of Campto colorectal cancer therapy

Sanofi-Synthelabo - Closing date of offer on Aventis postponed

Scripps Research Institute - Key to cell motility discovered

Scunthorpe General Hospital - Anesthetic assessment of morbidly obese patients reported

Sichuan University - Dentists turn to ERT to promote bone healing around dental implants

Simulations Plus, Inc. - Simulation software developer reports preliminary financial estimates

Spherix, Inc. - JECFA removes limit on daily tagatose consumption

St. Jude Children's Research Hospital, Memphis - Sts-1 and -2 proteins regulate TCR signaling

State University of New York Buffalo - Liposome-associated drugs exploit the presence of tumor vessels

Technical Insights - Biocompatibility to widen the scope of biomaterial applications

Therion Biologics Corporation - Phase III trial to study PANVAC-VF in advanced pancreatic cancer

Thomas Jefferson University - The high affinity phage PHH2 will improve hepatitis B virus screening

Tokyo Med & Dent. University - B cells may trigger intestinal inflammation in inflammatory bowel disease

Tokyo Metropolitan Inst. of Neuroscience - Hepatitis C virus type 2a subgenomic replicons thrive in human liver cells

Tottori University - Cell cycle promotion sensitizes lung cancer cells to paclitaxel

Tottori University - HSC-39 cells capture the significance of Epstein-Barr virus in gastric cancer

U.S. Food & Drug Administration - Infrared methodologies for trans fat determination reviewed

Umea University - Onlay bone grafts with implants effective for severely resorbed maxillae

UnitedHealth Group - Medicare-approved U Share Prescription Drug Discount Card announced

Univ. London Imperial College - Pro- and anti-inflammatory cytokines differentially regulated by PKC isoforms

Univ. of California, Los Angeles - The weight loss supplement usnic acid may lead to liver failure

Univ. of California, San Diego - Antigen-immunostimulatory oligonucleotide conjugates reviewed

Universite Louis Pasteur - E2F1-/- mice exhibit impaired beta cell mass and function

Universite de la Mediterranee - Multiple sclerosis associated with neurofibromatosis type I

University College Dublin - Apical membrane receptors in intestine are targets for vaccine delivery

University College London Hospitals - Cardiac monitoring essential in patients with blood disorder

University at Buffalo - Large abdomen can reduce men's lung function by 15%

University of Alberta - Graft dysfunction may lead to hepatic steatosis after islet transplantation

University of Alberta - Translating cardiovascular research in clinical practice

University of Arizona - p300/CBP-associated factor is a p53 target in breast tumors

University of Arkansas of Medical Science - Hyperglycemia plays role in early hyperalgesia in diabetic rats

University of Basel - Role of oligomerization domains in thrombospondins outlined

University of Bochum, Germany - Electrochemical sensor for the uncomplicated detection of "hits" on DNA chips

University of Bristol - Brain emboli dissemination after captive bolt stunning can spread BSE in animal

University of Burgundy - Food packaging materials disrupt androgen activity in breast cancer cells

University of California San Diego - Lentiviral and MLV based retroviral vectors for gene transfer elucidated

University of Chicago - Values from thoracic CT scans of mesotheliomas lean towards congruence

University of Cologne - Utility of auditory brainstem implants reviewed

University of Delaware - CIEF-RPLC-MS protein analysis system developed

University of Florence - TT virus can replicate in bone marrow as well as in the liver

University of Florida - Scientists correct muscle disorder in mice by delivering gene therapy to womb

University of Freiburg Clinic - FHL2 is expressed in human ovarian cancer cells

University of Gothenburg - Chondrosarcomas lack tumor-specific chromosome changes

University of Hospital Munster - S100-beta increases in marathon runners reflect extracranial release

University of Liverpool - -RFamide peptides and effects on feeding behavior reviewed

University of Maryland - Furin processing likely mechanism for inactivating extracellular HIV-1 Tat

University of Michigan - CC-chemokine levels lack correlation with HIV-1 stage and response to treatment

University of Michigan - Early exposure to dexamethasone has long-lasting effects on neurodevelopment

University of Michigan - Novel model allows analysis of molecular pathogenesis of neuronal degeneration

University of Michigan - Regular physical activity reduces health care costs among employees

University of Michigan Health Systems - Prevalence of P. carinii mutations increased in the United States

University of Munich - Proteomics-based screen identifies disease-associated humoral antigens

University of Newcastle-Upon-Tyne - RAG-1 is a suitable mouse model for mitochondrial DNA disease

University of North Carolina - Metabolism of P2 receptor agonists aids cystic fibrosis research

University of North Carolina - Mothers' fish consumption can boost children's development

University of North Carolina - Thirteen football players died during 2003 season, none from heatstroke

University of North Texas - Rat study provides neuropathological basis for dementia, AD in females

University of Palermo - Activation-induced cell death in T cells reduced in diabetic patients

University of Pennsylvania - Adiponectin acts in the brain to decrease body weight

University of Pittsburgh - Investigational treatment for Alzheimer disease to be tested in humans

University of Rome La Sapienza - Insular phenotypes suggest unfavorable outcomes for thyroid carcinoma patients

University of South Carolina - Weight-management practices among adolescents determined

University of Texas SW Medical Center - Bacteria spill their guts to aid researchers in quest for new antibiotics

University of Tokyo - Heat shock protein 60 is important for hepatitis B virus protein activity

University of Tokyo - Microarray analysis reveals NOL8 overexpression in diffuse gastric cancer

University of Toronto - Smoking doesn't affect disease risk in carriers of BRCA mutations

University of Vermont - ALL survivors bear genetic damage from life-saving chemotherapy

University of Vienna - Microvessel density is not essential for scintigraphic imaging of brain tumors

University of West Florida - IL-18 may affect B-cells through paracrine actions

VA Palo Alto Health Care System - Post-traumatic stress disorder in women linked with poor health

VivoMetrics, Inc. - LifeShirt System used in study of sickle cell anemia and nocturnal hypoxia

Wake Forest University - Radiofrequency ablation spares kidney, kills tumor

Wake Forest University - Surprising finding could lead to new CF treatment

Watson Pharmaceuticals, Inc. - Health Canada approves OXYTROL for the treatment of overactive bladder

Wayne State University - Differential cell killing by lymphomagenic MLV independent of p53 activation

White Mountain Capital - Telik downgraded to HOLD by independent researcher

World Heart Federation - Organization makes global plea to tackle CVD

Yale University - Notch ligands differentially instruct Th cell fate

Yale University - The Cre/lox system helps Wnt-targeted gene therapy destroy colorectal cancer

Yokohama City University - Renal epithelial neoplasms can be associated with familial tumor syndromes

Yonsei University - Diagnostic values of FUL and Q-tip angle are negligible