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Pharma Law Weekly

Susan Hasty, Publisher

Table of Contents . . . July 27th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Pharma Law Weekly | Other Publications

Abbott Laboratories - Pharmaceutical firm comments on Medicare project for self-injectable drugs

Acorda Therapeutics - Jane Wasman hired as executive VP, general counsel at pharmaceutical firm

Advanced Biotherapy, Inc. - Patent application submitted for acne treatment

Advancis Pharmaceutical Corporation - Keflex brand of anti-infective products acquired from Lilly

American Oriental Bioengineering, Inc. - Biotech company takes action to cease listing on Germany stock exchanges

Avanir Pharmaceuticals - Patient issued for asthma, allergy treatment

HIV/AIDS Prevention - Rights group says Thailand's drug war darkens its anti-AIDS success

Helsinn Healthcare SA - Palonosetron HCl injection poster presentations made at MASCC symposium

Institute of Research for Development - False or pirated antimalarial drugs freely obtainable in Cameroon

King Pharmaceuticals, Inc. - Pharmaceutical company considers legal recourse regarding Levoxyl Bioequivalence

Legal Issues - Defense makes closing argument in trial of drug company employees

Legal Issues - Former Gulf Shores, Alabama, doctor faces lawsuit over drug overdose

Ligand Pharmaceuticals Incorporated - Targretin cutaneous T-cell lymphoma therapy reimbursed by Medicare

Medarex, Inc. - Ability Biomedical Corporation acquired

drugstore.com, inc. - Lawsuit against drugstore.com alleges financial misrepresentation

INSERM 412, Lyon - HCV Core protein potent nucleic acid chaperone similar to retroviral NC proteins

ProxyMed, Inc. - Key Electronics contracting manufacturing business sold

Aastrom Biosciences, Inc. - Biotech company appoints James A. Cour as president, COO

Acadia Pharmaceuticals, Inc. - Favorable results presented from phase Ib/IIa trial of ACP-103

Acambis plc - David Lawrence named CFO at pharmaceutical firm

Adherex Technologies, Inc. - FDA clears IND for Exherin

Adolescent Health - Girls more likely than boys to be overexposed to alcohol ads in magazines

Advanced Magnetics, Inc. - Response submitted to FDA on approvable letter for Combidex

Akers Biosciences, Inc. - Monitoring system launched for airborne biowarfare agents

Albert Einstein College of Medicine - CD81 assists the entry of hepatitis C virus into liver cells

Amgen - Phase II study of GDNF fails to meet primary endpoint

Andromed, Inc. - Medical device company reports product development milestones

Applera Corporation - Cancer therapeutics alliance formed

Archemix Corp. - IND submitted for thrombin inhibitor, ARC183

Arizona State University - Hepatitis B antigen fusions expressed in Agrobacterium system

BIOflex Medical Magnetics, Inc. - Positive results reported from new magnet study

BPRC, Rijswijk - Progenipoietin-1 increases plasmacytoid/myeloid dendritic cells in SIV-infection

Baylor College of Medicine - EBV viral load monitoring best used to enable prompt treatment of PTLDs

Baylor Institute of Immunology Research - Immunity may be a dynamic system driven by two sets of opposite vectors

Biomet, Inc. - Device firm reports record fourth quarter, fiscal year end results

Breast Cancer - Study characterizes carcinoma arising from pre-existing PLH and CHH lesions

Brigham & Women's Hospital - Stress from caregiving isn't a risk factor

Burnham Institute - Research uncovers crystal structure for cell binding complex

Butantan Institute, Sao Paulo -  Escherichia coli vectors host the synthesis of recombinant human interferon

Cancer Treatment - Rare cancer overpowers a brave young girl

Cellomics, Inc. - GE Healthcare collaborates to provide improved cellular screening

Cent. Food Tech. Res. Inst., Karnataka - Spice phenolics inhibit human PMNL 5-lipoxygenase

Children's Hospital, Boston - Endostatin requires E-selectin for angiogenesis inhibition

China Pharmaceuticals Corp. - Company launches liquid, all-natural multivitamin

Chinese University of Hong Kong - Individualized counseling by a pharmacist helps treatment outcomes

Columbia Laboratories, Inc. - MRP submissions announced for Striant SR

Cornell University - Moderate obesity reduces mortality after coronary intervention

Curie Institute, Paris - Amplifications in chromosome arm 1p identified

Cutting Edge Information - Oncology drugs dominate pharmaceutical pipelines

Cutting Edge, Information - Pharmaceutical companies invest nearly $1 billion on sales forces, study shows

Duke University - Hematopoietic SC dose correlates with speed of immune reconstitution after SCT

EMD Chemicals - Chemical company selects Zemeter software from Supply Chain Consultants

Encision, Inc. - Device company announces new CEO/president

Ethiopian Health & Nutrition Research Inst. - Polymerase chain reaction repudiates microscopic analyses of enteric amoebas

Federal University of Sao Paulo - Paradoxical sleep deprivation affects some cardiovascular risk in aged rats

Food Poisoning - Tips offered on prevention, symptoms, and treatment of food poisoning

Forbes Medi-Tech Inc - Company announces increase in revenue guidance based on growth in sterol sales

Frost & Sullivan Americas - Need to integrate PACS with existing systems challenges vendors

Georgia State University - 5-HTP enhances serotonin content in serotonergic and non-serotonergic neurons

Guilford Pharmaceuticals, Inc. - William F. Spengler becomes CFO of GLIADEL-Wafer maker

HIV/AIDS Trend - Man lobbies for AIDS Awareness in India

Harvard University - C-reactive protein levels differ among U.S. women of various ethnic groups

Harvard University - Floating collagen gels support phenotypic variety in large vessel endothelia

Harvard University - Self-reactive T cells committed to innate immune cell lineage

Harvard University - Static and dynamic effects of health policy described

Healthcare Coverage - Health advocates question insurer's investments

Healthwise, Incorporated - Saint Alphonsus' IT expert Leslie Kelly Hall joins Healthwise board of directors

Hemispherx Biopharma, Inc. - Clinical trial to study Ampligen in HIV/hep-C coinfected patients

Hopital Europeen Georges Pompidou - Gene polymorphisms and diabetic nephropathy relationship needs investigation

Hopital Pellegrin, Bordeaux - Antibodies isolated against core antigen of HBV in HIV-infected patients

Hoshi University - Multivariate spline interpolation improves pharmaceutical formulation

Hypochondria - Report: Hypochondria is serious, and treatment is available

IDEA AG - Milestone payment issued for completion of pain therapeutic clinical study

IDM - Biopharmaceutical company appoints vice president, director France

INC Research - CRO announces further expansion of its West Coast operations

Icagen, Inc. - Collaboration to develop and commercialize sickle cell disease treatment

Immunicon Corporation - CellSearch Epithelial Cell Control Kit receives 510(k) clearance from FDA

ImmunoGen, Inc. - Preclinical data on huN901-DM1 in multiple myeloma published in cancer journal

Infodata Systems, Inc. - IT company building eDOCs system for American Red Cross Biomedical Services

InforMedix, Inc. - Alexander Miller joins scientific advisory board of Med-eMonitor maker

Inst. de Recerca Oncologica, Barcelona - Genetic studies in Spanish Wolfram syndrome families reported

Integrated BioPharma, Inc. - Paxis parent adopts stock repurchase plan

IntegriMED, Inc. - Growth accelerates in sales of EMR programs

Inverness Medical Innovations, Inc. - Diagnostics developer ships new over-the-counter ovulation, pregnancy tests

Inyx, Inc. - Contract awarded for development of non-ozone depleting HFA asthma spray

Johns Hopkins University - Combination therapy for chronic hepatitis C produces hemoglobin changes

Johns Hopkins University - Two regimens found comparable in preventing perinatal transmission of HIV

Kalorama Information - $12B cosmetic-aesthetic medicine market booms

Kansai Medical University - Laryngeal tube cuff pressure changes characterized

Katholieke University of Leuven - ViroSeq HIV-1 Genotyping System has decreased performance with non-B subtypes

Keddem Bioscience, Ltd. - Compugen establishes small molecule drug-discovery subsidiary

KetoCytonyx, Inc. - KTX 0101 studied for prevention of cognitive impairment in CABG surgery patients

Kyushu University, Fukuoka - HSC source should be considered based on data for individual ethnic populations

LAM Pharmaceutical, Corp. - LAM IPM Wound Gel launched in Panama City

LifePoint, Inc. - Drug diagnostic technologies company announces financial results

Louisiana State University - Vaccine risk/benefit communication high among public health clinics

Lux Research, Inc. - Nanotech research firm hires Matthew Nordan as VP, research

M.D. Anderson Cancer Center - ChIP microarrays can identify genes silenced in cancer

Manhattan Pharmaceuticals - Natural hormone may be key to appetite suppression, obesity control

Marshfield Med. Research Fdn. - Agrochemicals, lawn-care pesticides induce developmental toxicity mouse embryos

Massachusetts General Hospital - Nucleotide insertions reverse the cystic fibrosis phenotype in tissue cultures

Mayo Clinic - Newer treatments improve clinical outcome after myocardial infarction

Mayo Clinic - Researchers identify gene regulating aging and fertility

McMaster University - Better information needed about herb-drug interactions

MedCare USA - Local drug discount card provider launches web site

Medical Services International Inc. - Regulatory approval sought for VScan TB and Hep B test kits

Memorial Sloan-Kettering Cancer Center - HIV-1 Gag signal promotes interaction with cellular endocytic machinery

Mental Health Grant - NIH grant for post-disaster mental health treatment

Merck & Co., Inc. - Nitric oxide-enhancing COX-2 inhibitor advances into phase II clinical testing

Merck & Company, Inc. - Crystal structure of human phosphodiesterase 3B determined

Merrion Pharmaceuticals, Inc. - Pharmaceutical company appoints new members to management team

Michael J. Fox Foundation - Foundation gives $2 million for Parkinson research

Micromet AG - Single-chain antibody compounds generated for inflammatory, autoimmune diseases

Miravant Medical Technologies - FDA grants expedited review status for laser used to treat macular degeneration

Mylan Pharmaceuticals - FDA supports broader access to lower-priced drugs

NOP World Health - France has highest percentage of patients suffering from depression, anxiety

NYU - New hypothesis on the pathogenesis of syringomyelia is revealed

Nagoya City University - c-MPL gene mutations generate familial essential thrombocytosis

Nastech Pharmaceutical Company Inc. - Pharmaceutical company raises $12.5M through sale of common stock

National Bureau of Economics Research - Economic analysis of adult obesity published

National Inst. of Infectious Diseases, Tokyo - Novel cell-free reaction system studies fusion/entry mechanisms of HIV-1

Naval Medical Center, San Diego - Epidemiology of coccidioidomycosis elucidated

NeighborCare, Inc. - Institutional pharmacy provider names Richard W. Hunt CFO

New England Biolabs - Scientists develop a better way to copy DNA

New York University - Topical vascular endothelial growth factor hastens diabetic wound healing

New York University School of Medicine - Adenosine A2A receptor activation supports wound neovascularization

Novo Nordisk, A/S - Trial: NovoSeven effective in treatment of ICH

Omnicare, Inc. - Provider of pharmaceutical care extends tender offer for NeighborCare

Ondine Biopharma Corporation - Biopharma company completes CDN $16.9 million private placement

Oregon State University - Pyrrolizidine alkaloid metabolism characterized in different rat strains

Oregon State University - Study identifies genetics of fat metabolism, red wine link

Organon International - FDA finds gepirone ER not approvable for depression

Oxford University - New bone marrow transplant protocol spares recipient's immune system

PRA International, Inc. - Clinical development organization adds central nervous system experts

Pan American Health Organization - Mexico health minister calls rotavirus "major public health priority"

Par Pharmaceutical Companies, Inc. - NDA submitted as treatment for weight loss in AIDS patients

Phoenix Biosciences, Inc. - U.S. patent granted for immunological method that claims to reduce HIV activity

Picis, Inc. - Surgical Information Systems and Capsule Technologie sued for infringement

Point Therapeutics, Inc. - Phase 2 clinical trial studying anti-tumor activity of Talabostat initiated

Pri-Med Institute - Study shows eCME is the preferred learning channel for only 1 physician in 10

QMed, Inc. - Disease management services company announces second quarter results

QuadraMed Corporation - Healthcare information technology provider acquires Tempus Software

Qualyst, Inc. - Technology company announces formation of business advisory board

Quintiles Transnational Corp. - Quintiles appoints cardiac safety medical director

Respironics, Inc. - Offer to purchase outstanding shares of Profile Therapeutics accepted

Rockefeller University - Novel secreted enzyme from E. faecalis may cause pathogenesis and persistance

Samaritan Pharmaceuticals, Inc. - Thomas Lang joins Samaritan team as chief drug-development officer

Schaper & Brummer Co. - Black cohosh extract doesn't induce endometrial tumor growth in rat study

Schatz & Nobel, P.C. - Class action lawsuit against Hanger Opthopedic Group, Inc.

Schering Health Care Limited - British women most likely to use sterilization, vasectomy for contraception

Schwarz Pharma - Mylan receives $37.5 million, settles disputes with KUDCo and related parties

Science Based Health - New HydroEye Plus Lutein relieves dry eye, enhances macular health

Scott + Scott - Securities class action suit filed against Genta Incorporated

Serologicals Corporation - AltaGen Biosciences acquired by biological products company

Serologicals Corporation - Stock trading program implemented at biotech company

Signet Laboratories, Inc. - Diagnostic to predict acute renal failure released

SkinMedica, Inc. - Rights to facial hair skin cream purchased by SkinMedica

Solvay Pharmaceuticals, Inc. - Solvay Pharmaceuticals files for FDA approval of irritable bowel syndrome drug

Sourasky Medical Center - Testing combined vitamin D analog and ERT may help prevent bone loss

SparkPeople.com - Ten things to do before starting a diet

Spotfire Inc. - Applied Biosystems to collaborate on human gene study with Spotfire

St. Bartholomew's Hospital, U.K. - Dose-intense triplet chemotherapy with PBPC support investigated

St. Jude Medical, Inc. - FDA approves high-voltage CRT-D device system

St. Louis University - Role of leptin in obesity reviewed

Stavanger University College - Filter for CPR-induced ECG artefacts evaluated

Sun Life Financial - Sun Life Financial introduces new survivorship policy

Symyx Technologies, Inc. - Symyx, Dow Chemical extend research collaboration

Tel Aviv University - Diffusion MRI sensitive to glutamate cell swelling-induced structural changes

Therapeutics - Sloan-Kettering to research positive health impacts of flower pollen extract

Thoratec Corporation - California Pacific Medical Center now a Heart Hope Center

Tokai University, Kanagawa - Plasma remnant lipoproteins can be surrogate markers of antemortem level

U.S. National Cancer Institute - Lack of diagnostic follow-up may reduce mammography screening effectiveness

U.S. National Institutes of Health - Children's Environmental Health Center will address Tar Creek exposures

U.S. National Institutes of Health - Severe cGVHD characterized by high CD4+ cells relative to central memory cells

U.S. Natl. Committee for Quality Assurance - New survey measures women's satisfaction with their primary healthcare

Univ. Nacional Autonoma de Mexico, Mexico City - Jak 3 absence affects T-cell development

Univ. of Ag. Science Bangalore - Mechanism of HPV oncogene regulation of tumorigenesis described

Univ. of Alabama, Birmingham - Ancient vertebrate has vastly different immune system than humans

Univ. of California, Davis - Hypervariable epitopes induce immune responses against papillomaviruses

Univ. of Texas, Austin - Principles of transmucosal delivery of therapeutic agents outlined

Univ. of Wisconsin, Madison - As humans alter land, infectious diseases follow

Universidade Federal de Minas Gerais - BCG lymphadenopathy detected in a BCG-vaccinated infant

Universidade de Sao Paulo - IFNAR1-mRNA expression in PBMC associated with IFN-alpha response to hepatitis C

University Hospital Geneva - Defibrotide given in addition to heparin may be efficient prophylaxis for VOD

University Hospital, Magdeburg - ADMA metabolism not affected by homocysteine or lipid levels

University of Athens - Raloxifene/atorvastatin combination significantly effects serum lipids

University of Brighton - Materials for microspheres for sustained release identified

University of Bristol - Understanding MMPs and cadherins may help prevent atherosclerosis

University of Buenos Aires - DPT schedule evokes Th2 tetanus and Th1 pertussis immune responses

University of California, Davis - Extended daily dialysis safe and effective

University of Cambridge - Could skin cells become brain cells?

University of Cincinnati - Bead-based electrochemical immunoassay developed for detecting bacteriophage MS2

University of Cincinnati - Neuropeptide Y regulated by c-fos in murine dentate gyrus

University of Cologne - Iris pigment epithelial cells show promise as neurotrophic gene vectors

University of Crete - Depression and adipose alpha-linolenic acid negatively correlated

University of Erlangen-Nurnberg - Loteprednol has durable effects without endocrine disruption

University of Halle-Wittenberg - Melanocytes express 3G5 surface antigen

University of Hawaii - High STD rates among females in juvenile detention warrant routine screening

University of Hong Kong - Ducks in southern China maintained potentially pandemic strains of influenza

University of Hong Kong - P73 expression associated with cellular radiosensitivity after radiotherapy

University of Illinois - Actin cytoskeleton disruption complements Nef enhancement of HIV-1 infectivity

University of Karlsruhe - Effects of bisphenol A on fibroblasts characterized

University of London - Imaging technology differentiates lesions, provides tumor biology insight

University of Lyon - DNA flow-thru chip used for typing and subtyping of influenza viruses

University of Michigan - Lifestyle changes can help prevent prostate cancer

University of Michigan - Pediatricians are plentiful, but not in poorer states

University of Missouri - Chromatography technique can be applied to anti-cancer drugs

University of Nebraska - Home deaths unnecessarily costly, burdensome for families

University of Nijmegen - In situ tumor ablation creates antigen source for antitumor immunity induction

University of Pennsylvania - Erythropoietin gene therapy causes autoimmune anemia in animal studies

University of Pittsburgh - Pitt to establish center that will use viruses to trace nervous system circuitry

University of Scranton - Green and black teas inhibit atherosclerosis in hamsters

University of Sydney - Australia should introduce vaccine injury compensation scheme

University of Texas Southwestern - Access to DNA secrets yields better understanding of genes

University of Texas Southwestern - Protein controls acid in cells by direct detection of volume changes

University of Tsukuba - Carotid arterial baroreflex dynamic response limits orthostatic hypotension

University of Turin - The dopamine D2 receptor gene is not involved in migraine symptomatology

University of Turku - Interferon gamma is essential for Th1 cell differentiation

University of Ulsan - Left bundle branch block can have systolic and diastolic asynchrony

University of Uppsala Hospital - Immunosuppressives effect on graft-derived fibroblasts contribute to benefit

University of Wollongong - The transfectant pDMAEMA does not disrupt endosomes after internalization

University of York - Studies show N-lithocholyl insulin to be new, prolonged-acting insulin

Vanderbilt University - Human genomics may affect the management of patients with arrhythmias

Varian Medical Systems - Emory pioneers robotic system for precision radiation treatments

Vaxin Inc. - Biotechnology company announces appointment of new board member

Ventracor - VentrAssist pilot trial 12-month update

Vertex Pharmaceutical, Cambridge - Novel HIV inhibitors generated through hybridization of known ligands

Vertex Pharmaceuticals, Inc. - Companies agree to develop and commercialize VX-680 for cancer

Victoria Heart Institute Foundation - Transradial coronary intervention is preferred for patients older than 80

Wake Forest University - Utility of cryosurgery for common skin conditions reviewed

Wayne State University - TIMP-1 protects against Pseudomonas aeruginosa-induced corneal destruction

WellPoint Health, Networks Inc. - Anthem-WellPoint pending merger approved by shareholders

Windhover Information, Inc. - Study: Healthcare entrepreneurs want more than initial funding from VC firms

World Health Organization - Syringes disposed of safely after millions vaccinated

Yale University - Bone marrow cells can produce epithelial cells without fusion

Yale University, New Haven - Unrecognized hypervolemia in chronic heart failure is related to poor outcomes

eResearchTechnology - SFBC International enters integrated technology and services solution agreement

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