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Pharma Law Weekly

Susan Hasty, Publisher

Table of Contents . . . August 17th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Pharma Law Weekly | Other Publications

Ablynx - Nanobody drug discovery and development partnership signed

CardioGenesis Corp. - Medicare panel's review of myocardial revascularization complete

Collaborations - Gold Standard, ACP to integrate and market Clinical Pharmacology, PIER Products

Cutting Edge Information - Generic drug sales to exceed $60 billion by 2007

Exeter Life Sciences - ViaGen parent establishes biotech IP, licensing, and investment division

Genetronics Biomedical Corp. - Tumor-focused biomedical company wins another electroporation patent

Kaiser Family Foundation - Study examines Medicare drug cards

Legal Issues - "Cancerphobia" lawsuits out of proportion to actual breast cancer risk

Legal Issues - Invacare Corporation files patent infringement lawsuit for SureStep technology

Legal Issues - Wyeth wins one diet drug lawsuit, settles another

Mental Health - New Hampshire state prisoners sue for better mental health care

Pennsylvania Attorney General - State attorney general says consumers will receive $1.6 million drug settlement

Phoenix Biosciences, Inc. - Patent issued for immunological method to reduce HIV activity

Prescription Drugs - GlaxoSmithKline criticizes decision to hear pricing complaint on AIDS drug

Prescription Drugs - Louisiana state organizations working to publicize Medicare drug cards

- Sun Life Financial restructures group insurance sales organization

Health Management Associates, Inc. - HMA reports record Q3; earnings per share increases 20%

3M - Alliance to bring electronic dry powder inhaler technology to market

AOP Orphan Pharmaceuticals - Thromboreductin registrations obtained in central Europe

Academic Medical Center, Amsterdam - VF undersensing possible with optimal R wave sensing during sinus rhythm

Acambis Research Ltd. - Neurotropic disease incidence very low after yellow fever vaccine

Access Pharmaceuticals, Inc. - Product development activities OraDisc product candidates provided

Access Pharmaceuticals, Inc. - Update provided on polymer platinate AP5346

Addenbrooke's Hospital, Cambridge - Expression profiling of the Leishmania life cycle conducted

Alfred Hospital, Melbourne - Infection control measures should guide methicillin-resistant S. aureus control

AmeriHealth Mercy Health Plan - Health plan offers scholarship to nine members

American Heart Association - Panel develops sports guidelines for youth with genetic cardiovascular diseases

Amgen, Inc. - Biotech company reports $0.49 per share earnings

Applera Corp. - Celera, Seattle Genetics, to co-develop targeted antibody therapies for cancer

Avitar, Inc. - Diagnostics firm posts gain in number of new clients

Axon Neuroscience, Vienna - Folding of Alzheimer core PHF subunit characterized

Barr Pharmaceuticals, Inc. - Response submitted to FDA in support of OTC status for Plan B

Bavarian Nordic - FDA grants fast track designation for smallpox vaccine candidate IMVAMUNE

Bayer Biological Products - Pharmaceutical firm makes effort to combat product tampering, counterfeiting

Baylor College of Medicine - New gene associated with type 1 diabetes

Becton, Dickinson and Company - Medical technology company reports 8% increase in revenue

Beth Israel Deaconess Medical Center -  Pneumocystis activates AM NF-KB signaling through mannose receptors

Beth Israel Medical Center, New York - MRI and CT can visualize congenital heart disease

Bioject Medical Technologies, Inc. - Device firm reports 39% increase in revenues

Blue Cross & Blue Shield of Oklahoma - Oklahoma health plan enhances disease management program

Boston Life Sciences, Inc. - IND application filed for Axosine for stroke recovery

Breast Cancer - Selective estrogen enzyme modulator therapy in postmenopausal disease reviewed

Brown Medical School - Brown and Harvard team identifies potential target for obesity drugs

Business Update - Health Alliance signs contract for MEDai's predictive modeling solution

Canadian Institutes of Health Research - Canadians join international registration of randomized controlled trials

Cancer Genetics - Missense mutations frequently perturb BRCA-1 protein

Cardiac Science, Inc. - Defibrillator reports continued strength of AED sales

Catholic University of Korea - Photodynamic therapy causes plasma membrane damage in cancer tumor cells

Cerberus Capital Management, LP - GenCorp signs definitive agreement to sell automotive business

Chaim Sheba Medical Center, Tel Hashomer - Mutation D30N not selected by HIV-1 subtype C in nelfinavir resistance

Children's Hospital, Cincinnati - Transcription factor AP-2alpha plays key role in trophoblast differentiation

Chiron - Clinical trial begins for Procleix West Nile virus blood screening assay

Chiron Corp. - Record number of flu vaccines to be made

Christian Medical College, Vellore - Streptozotocin effect on ultrastructure of rat pancreatic islets determined

Chronic Fatigue Syndrome - Integrated approach necessary for CFS treatment

Ciphergen Biosystems, Inc. - Company launches ProteinChip System, Series 4000

Cleveland Clinical - Polymyalgia rheumatica: Clinical presentation is key to diagnosis and treatment

CollaGenex Pharmaceuticals, Inc. - Dental-focused pharmaceutical reports increased revenues, sales

Columbia University - Innate immune mechanisms likely thwart mother-to-child HIV-1 transmission

CompuMed, Inc. - Company wins California contract to provide remote ECG screening

Corgentech, Inc. - TF decoy technology company reports Q2 milestones, $10.6M revenue

Coronet Foods - No evidence of salmonella found at Roma tomato processor's facilities

Cutting Edge Information - Pharmaceutical product launches spur spending

Cylene Pharmaceuticals - Quadruplex regulates expression of c-Myc oncogene, adopts parallel-loop isomers

Dainippon Pharmaceutical Co. Ltd. - Novel compounds have antitumor activity

Dartmouth College School of Medicine - PKB/Akt activity, Ser473 phosphorylation regulated by PKCalpha

Dermatology - Hormones usually behind acne flare-ups in adult women

Dharmacon, Inc. - Genome-wide line of RNA assays for gene silencing measurement launched

Dimethaid Research, Inc. - FDA approves Penecure antifungal trial

Discovery Partners International, Inc. - Drug-discovery company reports 16% revenue increase in Q2

Endovasc, Inc. - Company concludes Liprostin phase II clinical trial

Enzo Biochem - GSK inks agreement for RNA/DNA labeling, detection, and amplification

EpiTan, Ltd. - Australian company acquires three dermatology products

Ethicon Endo-Surgery, Inc. - Two million procedures with Mammotome system marks major milestone

Fred Hutchinson Cancer Research Center - Study finds anti-HIV protein evolved millions of years before emergence of AIDS

Funding - Grant awarded to four medical research centers in South Dakota

GSF, Munich - eEPCs home to hypoxic lung metastases upon i.v. administration

Genomatica, Inc. - Computational systems biology company forms scientific advisory board

HIV/AIDS Treatment - Funding woes prompt HIV/AIDS care program to close enrollment

HSS, Inc. - Outpatient prospective payment system sales increase

Harvard University - Body mass index predicts mortality in kidney transplant recipients

Healthcare Coverage - Medicaid officials field questions in Mississippi governor's hometown

Healthpoint, Ltd. - Healthcare company names director of healthcare systems

Heart Research Institute, Sydney - Metabolic syndrome includes dyslipidemia

Hoffmann-La Roche Inc. - Co-infected HCV/HIV patients achieve sustained response with Pegasys and Copegus

Hokkaido University - Lumbar spine BMD associated with TNF gene polymorphisms in epidemiologic study

Hopital Bicetre, Le Kremlin Bicetre - Addition of tenofovir decreases AUC for atazanavir in HIV-treated patients

Hopital Purpan, Toulouse - Use of two HIV antibody screening tests increase false-positive rate

Hungarian Academy Science - The ABCG2 protein contributes to drug resistance but is a marker in gene therapy

INAMED Health - ADA encourages members to discuss obesity surgery with appropriate patients

INSERM - Anti-idiotypic scFv used as surrogate tumor antigen characterized

IRCCS, Rome - Hepatocytes promote expansion and differentiation of NK cells from SC precursors

IVAX Corporation - Pharmaceutical company receives FDA final approval for fluconazole tablets

Idun Pharmaceuticals, Inc. - Phase II clinical study initiated for IDN-6556 in hepatitis C

ImClone Systems Incorporated - SBLA filed with FDA for Erbitux in head and neck cancer

Infectious Diseases - African office of clinical trials collaborative partnership opened

Insmed Incorporated - Biopharmaceutical company reports second quarter financial results

Institute Pasteur, Paris - Bipotential embryonic liver stem cells contribute to liver regeneration

Instituto Evandro Chagas - Clinical features of American cutaneous leishmaniasis reviewed

Integra LifeSciences Holdings Corporation - KraniOS Cranial Closure System to launch

IntegraGen - Molecular diagnostics company appoints non-executive director

Inverness Medical Innovations, Inc. - Diagnostic products manufacturer announces second quarter 2004 results

Iowa State University - Exercise improves antibody response to influenza vaccine in elderly

Janssen Pharmaceutica Products, L.P. - Pharmaceutical company to appeal U.S. District Court decision on Sporanox patent

Johannes-Gutenberg-University - Vaccine protects against six diseases in infants

Johns Hopkins University - Human papillomavirus DNA vaccines compared

K.U. Leuven University - Scientist develops new surgical technique for laryngeal tumors

Karolinska Institute - Smoking linked to increased risk of chronic renal failure

KeyNeurotek AG - Drug development company announces new board members

Kinexus Bioinformatics Corporation - Published findings validate PLK1 as potential cancer drug target

Korea Advanced Institute Science & Technology - Method described for extracting large genomic fragments from human cells

Laser Diagnostic Technologies, Inc. - Laser maker reports record revenue growth

Locus Pharmaceuticals - Pharmaceutical companies to collaborate on diabetes drug design

Louisiana State University - Peptides found through phage display direct antigen to dendritic cells

MINRAD, Inc. - Medical device company to merge with Technology Acquisition Corporation

MWG Biotech AG - Biotech company announces global supply contract for oligonucleotides

Massachusetts General Hospital - Researchers identify better hepatitis C treatment for people with HIV

Max Planck Institute for Biophysical Chemistry - 3D structure of pre-catalytic spliceosomal complex B determined

Max-Planck-Institute for Infection Biology - Apoptosis paves path for T cell activation against bacteria

Mayo Clinic - Treatment causes short-term, modest delay in AD onset

Mayo Foundation - Scientists sacrifice normal cells to kill melanoma

Medical University of Berlin - Improved method devised for synthesis of peptides with free C termini

Medical University of Sofia -  Astragalus corniculatus saponins have antitumor effects in hamsters

Merck Research Laboratories, San Diego - Hepatic CYP isoforms inhibited by mGluR5 antagonists

Miguel Servet University Hospital - Long-term outcome of anatomic hip prosthesis evaluated

Milestone Venture Partners - Venture capital firm's investee receives $20 million commitment

Missouri Bone and Joint Center - Simplified ligament balancing technique developed

Molecular Insight Pharmaceuticals - Research shows expansion of amino acid chelate technology fluorescent microscopy

Mt. Sinai School of Medicine - Candidate topical microbicides exhibit several anti-HSV mechanisms

Myriad Genetics, Inc. - Biopharmaceutical company presents data on Alzheimer disease drug candidate

Nancy University Hospital - Arrhythmia detection by dual-chamber ICDs reviewed

Nastech Pharmaceutical Company Inc. - Pharmaceutical company announces second quarter financial results

National Association of Health Underwriters - NAHU supports legislation that will insure more Americans

Natl. Taiwan Univ. Hospital - Postmenopausal women with hyperprolactinemia may benefit from raloxifene

Neuro3d - Johnson & Johnson identifies candidate compound and extends collaboration

Northfield Laboratories Inc. - First interim analysis of polyheme ambulance study data announced

NuGEN Technologies - Cincinnati Children's Hospital implements RNA amplification and labeling system

Nymox Pharmaceutical Corp. - Study shows new use for AlzheimAlert test: distinguishing vascular cases

OAO HealthCare Solutions, Inc. - Information technology company adds document imaging capability

Orthofix - Orthopedic products company announces preliminary second quarter results

Osaka University - Akt phosphorylation is key event in induction of telomerase activity by E-2

Osaka University - WT1 peptide vaccine with BCG-CWS is efficient for tumor eradication

Ospedale Regina Margherita, Turin - Aberrant glycosylation in IgAN reviewed

Ovarian Tumors - Routine lymph node dissection unnecessary for low malignant potential tumors

Pacific Northwest National Laboratory - Yeast mating system improves Fab generation and display

Pain, Therapeutics, Inc. - Biopharmaceutical company announces second quarter financial results

Pancreatic Cancer - Mapping project to summarize pancreatic cancer research investment in U.S.

Partnership for Prevention - Groups commend expanded coverage of preventive services under Medicare

Pennington Biomedical Research Center - Interactions found between agouti-related protein and leptin

Pfizer - Pharma company releases financial report, business update

Polish Academy of Science - A novel gene mutation in congenital neuropathy described

Power3 Medical Products, Inc. - Rights to neurodegenerative disease blood test secured from Baylor

Praecis Pharmaceuticals Incorporated - Pharma company announces publication of preclinical data in Rheumatoid Arthritis

Prince Charles Hospital, Brisbane - Point-of-care testing shows variation in the degree of platelet inhibition

Purdue University - Stuttering more than talk - research shows brain's role in disorder

Quinton Cardiology Systems, Inc. - Cardiology products developer announces results for 3- and 6-month periods

Recom Managed Systems, Inc. - Ambulatory ECG system tested under the supervision of a third party review board

Research Dynamics Consulting Group, Ltd. - Contract research organization CEO receives Entrepreneur of the Year honors

Research and Markets - Analytical tool for studying R&D efforts available

Rheumatoid Arthritis - RheumMates lifestyle-coaching program launched for rheumatoid arthritis patients

Rightfield Solutions - Professional Casualty Association offers Web-based tool to lower malpractice

Rio de Janeiro State Univ. Hospital - HCV associated with diabetes after kidney transplant in patients on tacrolimus

Robarts Research Institute - Study identifies novel stem cell in blood and vessel formation

Roche Pharmaceuticals - New hepatitis B indication filed for PEGASYS filed in U.S., E.U. and Switzerland

Royal Victoria Hospital, Belfast - Optimal settings for Diprifusor propofol delivery determined

Russian Academy of Medical Sciences -  H. pylori typing methods compared

SCYNEXIS Inc. - U.S. National Institute on Drug Abuse awards contract to development company

Schwarzeck-Verlag, GmbH - Dendrite completes strategic acquisition of German company

Scripps Research Institute - Mouse model developed to evaluate of DNA minigene vaccines

Se-cure Pharmaceuticals Ltd. - Report finds Femarelle can safely and effectively relieve menopausal symptoms

Seoul National University - Cadalene extract exerts antioxidative effect on NNK-induced lung tumorigenesis

Sigma-Aldrich Corporation - Life science products company obtains CE Mark certification for E.U. sales

Signet Laboratories, Inc. - Drug company plans to develop sepsis and acute renal failure products

St. James University Hospital, Leeds - Sympathetic neural hyperactivity occurs after unstable angina and acute MI

St. Louis University - Status of live attenuated influenza virus vaccine in U.S. reported

State University of Campinas - Child-Pugh classification predicts survival better than MELD in liver transplant

Sterling Financial Investment Group, Inc. - Financial investment group hires senior biotech analyst

Sting-Free - Tech company's new insole composite can block plantar fasciitis heel pain

TechniScan, Inc. - Stephen Blum joins ultrasound company's board

Tenet Healthcare Corporation - Tenet sells hospital assets of Redding Medical Center to Hospital Partners

TheraQuest Biosciences - Entities invest in bioscience company's development of pain management drugs

Thermo Electron Corp. - DPC inks agreement for TCAutomation and Konelab

Trinity Partners - Data solutions group to provide services for biotechs and pharmaceuticals

Tufts University - More than half of hospitalized stroke patients likely treated against guidelines

U.S. Department of Agriculture - Real-time RT-PCR applied for quantitation of avian influenza virus

U.S. Food & Drug Administration - RNA interference protects against lethal influenza virus challenge

U.S. Food & Drug Administration - Tissue partitioning of endotoxin for pharmacokinetic modeling determined

U.S. National Institutes of Health - Astrocytes contribute to retroviral neuropathogenesis through MCP-1 generation

U.S. National Institutes of Health - Pediatric patients require higher dosages of i.v. voriconazole than adults

United Soybean Board - New research shows shift in opinion on obesity epidemic

Univ. of Illinois, Urbana-Champaign - Isolated soy protein shown to benefit type 2 diabetics

Univ. of Texas SW Medical Center - Lipodystrophies are rare disorders causing metabolic syndrome

Universidade Federal do Rio de Janeiro - Pressure-inactivated foot-and-mouth disease virus is vaccine candidate

University Children's Hospital, Heidelberg - Glucocorticoid receptor inactivation in hepatocytes leads to hypoglycemia

University College London - DNA immunization achieved with plasmids expressing hCG beta-chimeras

University Medical Center, Utrecht - Cryptococcal glucuronoxylomannan disrupts endothelial neutrophil rolling

University Medical Polyclinic, Bonn - Nck-interacting proteins identified in vascular smooth muscle cells

University of Barcelona - Immune recovery slows after 3 years HAART and reaches plateau after 4-5 years

University of Basel Hospital - Persistent apoptosis in HIV patients associated with poor recovery of CD4 cells

University of California, San Francisco - Heart disease and cardiovascular malformations can occur in utero

University of Cincinnati - Effect of ingested fat on satiety reviewed

University of College London - ESHAP regimen cytoreduces resistant myeloma patients

University of Essen, Germany - Combination anticlotting therapy increases risk of bleeding

University of Groningen Hospital - Short-term smoke exposure attenuates ovalbumin-induced airway inflammation

University of Hong Kong - One-step quantitative RT-PCR assay detects SARS coronavirus

University of Hong Kong - Pathogenic role suggested for eukaryotic initiation factor oncogene

University of Ljubljana - Researchers develop an improved, automated 24-hour electrocardiogram device

University of Medicine, Berlin - Viruses may trigger heart disease, which can be followed by cardiomyopathy

University of Michigan - Endothelial nitric oxide synthase is protective in mice

University of Nebraska - Efficacy of external cardioversion waveforms compared

University of Regensburg - FasL-overexpressing dendritic cells purge activated T cells

University of Rotterdam - Barrett neuroendocrine cells have prognostic value in GEJ adenocarcinoma

University of Saarland - Antigenic peptide derived from cancer-testis antigen NY-ESO-1

University of Siena - Flk-1 target gene identities could elucidate vasculo-, angiogenesis pathways

University of Tokyo - Microfluidic PDMS bioreactor developed for large-scale culture of hepatocytes

University of Utrecht - Novel peptides inhibit SARS coronavirus

University of Washington - Gene therapy reaches muscles throughout the body and reverses MD in animal model

University of Washington - UW to lead most comprehensive study of air pollution and cardiovascular disease

Vanderbilt University - Nuclear import inhibition counters staphylococcal enterotoxin B

Varian Medical Systems - New treatment planning tools added to Eclipse radiotherapy software

Velcura Therapeutics, Inc. - Development of new DNA microarray to help speed bone disease research announced

Vernalis, Ltd. - Severe headaches more likely to occur around menstruation

Vical Incorporated - Phase 1 clinical trial with bivalent anthrax vaccine initiated

Virginia Bioinformatics Institute - Proteomic research centers target bioterrorism agents

Vital Living Inc. - Nutrition-focused company introduces first organic nutrition bar

Waters Instruments, Inc. - Medical instrument company named to Fortune's Top 100 List

Weill Cornell Medical College - Discovery of gene may mean stem cells exist in heart

Whitehead Institute for Biomedical Research - High-performance DNA multilane microdevice system developed

Wyeth Pharmaceuticals - Agreement reached in national diet drug settlement

Yamanouchi Pharmaceutical Co. Ltd - Novel 5-HT2c receptor agonist possesses anti-obesity activity

Yellowstone Neurosurgical Associates - Getting relief from pain can be shocking

Yonsei University, Seoul - Estrogen receptor associated with epithelioid variants of renal angiomyolipoma

York University - Protein expression profiling malignancies reveals new tumor marker

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