Susan Hasty, Publisher
Table of Contents . . . August 17th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Pharma Law Weekly | Other Publications
Ablynx - Nanobody drug discovery and development partnership signed
CardioGenesis Corp. - Medicare panel's review of myocardial revascularization complete
Collaborations - Gold Standard, ACP to integrate and market Clinical Pharmacology, PIER Products
Cutting Edge Information - Generic drug sales to exceed $60 billion by 2007
Exeter Life Sciences - ViaGen parent establishes biotech IP, licensing, and investment division
Genetronics Biomedical Corp. - Tumor-focused biomedical company wins another electroporation patent
Kaiser Family Foundation - Study examines Medicare drug cards
Legal Issues - "Cancerphobia" lawsuits out of proportion to actual breast cancer risk
Legal Issues - Invacare Corporation files patent infringement lawsuit for SureStep technology
Legal Issues - Wyeth wins one diet drug lawsuit, settles another
Mental Health - New Hampshire state prisoners sue for better mental health care
Pennsylvania Attorney General - State attorney general says consumers will receive $1.6 million drug settlement
Phoenix Biosciences, Inc. - Patent issued for immunological method to reduce HIV activity
Prescription Drugs - GlaxoSmithKline criticizes decision to hear pricing complaint on AIDS drug
Prescription Drugs - Louisiana state organizations working to publicize Medicare drug cards
- Sun Life Financial restructures group insurance sales organization
Health Management Associates, Inc. - HMA reports record Q3; earnings per share increases 20%
3M - Alliance to bring electronic dry powder inhaler technology to market
AOP Orphan Pharmaceuticals - Thromboreductin registrations obtained in central Europe
Academic Medical Center, Amsterdam - VF undersensing possible with optimal R wave sensing during sinus rhythm
Acambis Research Ltd. - Neurotropic disease incidence very low after yellow fever vaccine
Access Pharmaceuticals, Inc. - Product development activities OraDisc product candidates provided
Access Pharmaceuticals, Inc. - Update provided on polymer platinate AP5346
Addenbrooke's Hospital, Cambridge - Expression profiling of the Leishmania life cycle conducted
Alfred Hospital, Melbourne - Infection control measures should guide methicillin-resistant S. aureus control
AmeriHealth Mercy Health Plan - Health plan offers scholarship to nine members
American Heart Association - Panel develops sports guidelines for youth with genetic cardiovascular diseases
Amgen, Inc. - Biotech company reports $0.49 per share earnings
Applera Corp. - Celera, Seattle Genetics, to co-develop targeted antibody therapies for cancer
Avitar, Inc. - Diagnostics firm posts gain in number of new clients
Axon Neuroscience, Vienna - Folding of Alzheimer core PHF subunit characterized
Barr Pharmaceuticals, Inc. - Response submitted to FDA in support of OTC status for Plan B
Bavarian Nordic - FDA grants fast track designation for smallpox vaccine candidate IMVAMUNE
Bayer Biological Products - Pharmaceutical firm makes effort to combat product tampering, counterfeiting
Baylor College of Medicine - New gene associated with type 1 diabetes
Becton, Dickinson and Company - Medical technology company reports 8% increase in revenue
Beth Israel Deaconess Medical Center - Pneumocystis activates AM NF-KB signaling through mannose receptors
Beth Israel Medical Center, New York - MRI and CT can visualize congenital heart disease
Bioject Medical Technologies, Inc. - Device firm reports 39% increase in revenues
Blue Cross & Blue Shield of Oklahoma - Oklahoma health plan enhances disease management program
Boston Life Sciences, Inc. - IND application filed for Axosine for stroke recovery
Breast Cancer - Selective estrogen enzyme modulator therapy in postmenopausal disease reviewed
Brown Medical School - Brown and Harvard team identifies potential target for obesity drugs
Business Update - Health Alliance signs contract for MEDai's predictive modeling solution
Canadian Institutes of Health Research - Canadians join international registration of randomized controlled trials
Cancer Genetics - Missense mutations frequently perturb BRCA-1 protein
Cardiac Science, Inc. - Defibrillator reports continued strength of AED sales
Catholic University of Korea - Photodynamic therapy causes plasma membrane damage in cancer tumor cells
Cerberus Capital Management, LP - GenCorp signs definitive agreement to sell automotive business
Chaim Sheba Medical Center, Tel Hashomer - Mutation D30N not selected by HIV-1 subtype C in nelfinavir resistance
Children's Hospital, Cincinnati - Transcription factor AP-2alpha plays key role in trophoblast differentiation
Chiron - Clinical trial begins for Procleix West Nile virus blood screening assay
Chiron Corp. - Record number of flu vaccines to be made
Christian Medical College, Vellore - Streptozotocin effect on ultrastructure of rat pancreatic islets determined
Chronic Fatigue Syndrome - Integrated approach necessary for CFS treatment
Ciphergen Biosystems, Inc. - Company launches ProteinChip System, Series 4000
Cleveland Clinical - Polymyalgia rheumatica: Clinical presentation is key to diagnosis and treatment
CollaGenex Pharmaceuticals, Inc. - Dental-focused pharmaceutical reports increased revenues, sales
Columbia University - Innate immune mechanisms likely thwart mother-to-child HIV-1 transmission
CompuMed, Inc. - Company wins California contract to provide remote ECG screening
Corgentech, Inc. - TF decoy technology company reports Q2 milestones, $10.6M revenue
Coronet Foods - No evidence of salmonella found at Roma tomato processor's facilities
Cutting Edge Information - Pharmaceutical product launches spur spending
Cylene Pharmaceuticals - Quadruplex regulates expression of c-Myc oncogene, adopts parallel-loop isomers
Dainippon Pharmaceutical Co. Ltd. - Novel compounds have antitumor activity
Dartmouth College School of Medicine - PKB/Akt activity, Ser473 phosphorylation regulated by PKCalpha
Dermatology - Hormones usually behind acne flare-ups in adult women
Dharmacon, Inc. - Genome-wide line of RNA assays for gene silencing measurement launched
Dimethaid Research, Inc. - FDA approves Penecure antifungal trial
Discovery Partners International, Inc. - Drug-discovery company reports 16% revenue increase in Q2
Endovasc, Inc. - Company concludes Liprostin phase II clinical trial
Enzo Biochem - GSK inks agreement for RNA/DNA labeling, detection, and amplification
EpiTan, Ltd. - Australian company acquires three dermatology products
Ethicon Endo-Surgery, Inc. - Two million procedures with Mammotome system marks major milestone
Fred Hutchinson Cancer Research Center - Study finds anti-HIV protein evolved millions of years before emergence of AIDS
Funding - Grant awarded to four medical research centers in South Dakota
GSF, Munich - eEPCs home to hypoxic lung metastases upon i.v. administration
Genomatica, Inc. - Computational systems biology company forms scientific advisory board
HIV/AIDS Treatment - Funding woes prompt HIV/AIDS care program to close enrollment
HSS, Inc. - Outpatient prospective payment system sales increase
Harvard University - Body mass index predicts mortality in kidney transplant recipients
Healthcare Coverage - Medicaid officials field questions in Mississippi governor's hometown
Healthpoint, Ltd. - Healthcare company names director of healthcare systems
Heart Research Institute, Sydney - Metabolic syndrome includes dyslipidemia
Hoffmann-La Roche Inc. - Co-infected HCV/HIV patients achieve sustained response with Pegasys and Copegus
Hokkaido University - Lumbar spine BMD associated with TNF gene polymorphisms in epidemiologic study
Hopital Bicetre, Le Kremlin Bicetre - Addition of tenofovir decreases AUC for atazanavir in HIV-treated patients
Hopital Purpan, Toulouse - Use of two HIV antibody screening tests increase false-positive rate
Hungarian Academy Science - The ABCG2 protein contributes to drug resistance but is a marker in gene therapy
INAMED Health - ADA encourages members to discuss obesity surgery with appropriate patients
INSERM - Anti-idiotypic scFv used as surrogate tumor antigen characterized
IRCCS, Rome - Hepatocytes promote expansion and differentiation of NK cells from SC precursors
IVAX Corporation - Pharmaceutical company receives FDA final approval for fluconazole tablets
Idun Pharmaceuticals, Inc. - Phase II clinical study initiated for IDN-6556 in hepatitis C
ImClone Systems Incorporated - SBLA filed with FDA for Erbitux in head and neck cancer
Infectious Diseases - African office of clinical trials collaborative partnership opened
Insmed Incorporated - Biopharmaceutical company reports second quarter financial results
Institute Pasteur, Paris - Bipotential embryonic liver stem cells contribute to liver regeneration
Instituto Evandro Chagas - Clinical features of American cutaneous leishmaniasis reviewed
Integra LifeSciences Holdings Corporation - KraniOS Cranial Closure System to launch
IntegraGen - Molecular diagnostics company appoints non-executive director
Inverness Medical Innovations, Inc. - Diagnostic products manufacturer announces second quarter 2004 results
Iowa State University - Exercise improves antibody response to influenza vaccine in elderly
Janssen Pharmaceutica Products, L.P. - Pharmaceutical company to appeal U.S. District Court decision on Sporanox patent
Johannes-Gutenberg-University - Vaccine protects against six diseases in infants
Johns Hopkins University - Human papillomavirus DNA vaccines compared
K.U. Leuven University - Scientist develops new surgical technique for laryngeal tumors
Karolinska Institute - Smoking linked to increased risk of chronic renal failure
KeyNeurotek AG - Drug development company announces new board members
Kinexus Bioinformatics Corporation - Published findings validate PLK1 as potential cancer drug target
Korea Advanced Institute Science & Technology - Method described for extracting large genomic fragments from human cells
Laser Diagnostic Technologies, Inc. - Laser maker reports record revenue growth
Locus Pharmaceuticals - Pharmaceutical companies to collaborate on diabetes drug design
Louisiana State University - Peptides found through phage display direct antigen to dendritic cells
MINRAD, Inc. - Medical device company to merge with Technology Acquisition Corporation
MWG Biotech AG - Biotech company announces global supply contract for oligonucleotides
Massachusetts General Hospital - Researchers identify better hepatitis C treatment for people with HIV
Max Planck Institute for Biophysical Chemistry - 3D structure of pre-catalytic spliceosomal complex B determined
Max-Planck-Institute for Infection Biology - Apoptosis paves path for T cell activation against bacteria
Mayo Clinic - Treatment causes short-term, modest delay in AD onset
Mayo Foundation - Scientists sacrifice normal cells to kill melanoma
Medical University of Berlin - Improved method devised for synthesis of peptides with free C termini
Medical University of Sofia - Astragalus corniculatus saponins have antitumor effects in hamsters
Merck Research Laboratories, San Diego - Hepatic CYP isoforms inhibited by mGluR5 antagonists
Miguel Servet University Hospital - Long-term outcome of anatomic hip prosthesis evaluated
Milestone Venture Partners - Venture capital firm's investee receives $20 million commitment
Missouri Bone and Joint Center - Simplified ligament balancing technique developed
Molecular Insight Pharmaceuticals - Research shows expansion of amino acid chelate technology fluorescent microscopy
Mt. Sinai School of Medicine - Candidate topical microbicides exhibit several anti-HSV mechanisms
Myriad Genetics, Inc. - Biopharmaceutical company presents data on Alzheimer disease drug candidate
Nancy University Hospital - Arrhythmia detection by dual-chamber ICDs reviewed
Nastech Pharmaceutical Company Inc. - Pharmaceutical company announces second quarter financial results
National Association of Health Underwriters - NAHU supports legislation that will insure more Americans
Natl. Taiwan Univ. Hospital - Postmenopausal women with hyperprolactinemia may benefit from raloxifene
Neuro3d - Johnson & Johnson identifies candidate compound and extends collaboration
Northfield Laboratories Inc. - First interim analysis of polyheme ambulance study data announced
NuGEN Technologies - Cincinnati Children's Hospital implements RNA amplification and labeling system
Nymox Pharmaceutical Corp. - Study shows new use for AlzheimAlert test: distinguishing vascular cases
OAO HealthCare Solutions, Inc. - Information technology company adds document imaging capability
Orthofix - Orthopedic products company announces preliminary second quarter results
Osaka University - Akt phosphorylation is key event in induction of telomerase activity by E-2
Osaka University - WT1 peptide vaccine with BCG-CWS is efficient for tumor eradication
Ospedale Regina Margherita, Turin - Aberrant glycosylation in IgAN reviewed
Ovarian Tumors - Routine lymph node dissection unnecessary for low malignant potential tumors
Pacific Northwest National Laboratory - Yeast mating system improves Fab generation and display
Pain, Therapeutics, Inc. - Biopharmaceutical company announces second quarter financial results
Pancreatic Cancer - Mapping project to summarize pancreatic cancer research investment in U.S.
Partnership for Prevention - Groups commend expanded coverage of preventive services under Medicare
Pennington Biomedical Research Center - Interactions found between agouti-related protein and leptin
Pfizer - Pharma company releases financial report, business update
Polish Academy of Science - A novel gene mutation in congenital neuropathy described
Power3 Medical Products, Inc. - Rights to neurodegenerative disease blood test secured from Baylor
Praecis Pharmaceuticals Incorporated - Pharma company announces publication of preclinical data in Rheumatoid Arthritis
Prince Charles Hospital, Brisbane - Point-of-care testing shows variation in the degree of platelet inhibition
Purdue University - Stuttering more than talk - research shows brain's role in disorder
Quinton Cardiology Systems, Inc. - Cardiology products developer announces results for 3- and 6-month periods
Recom Managed Systems, Inc. - Ambulatory ECG system tested under the supervision of a third party review board
Research Dynamics Consulting Group, Ltd. - Contract research organization CEO receives Entrepreneur of the Year honors
Research and Markets - Analytical tool for studying R&D efforts available
Rheumatoid Arthritis - RheumMates lifestyle-coaching program launched for rheumatoid arthritis patients
Rightfield Solutions - Professional Casualty Association offers Web-based tool to lower malpractice
Rio de Janeiro State Univ. Hospital - HCV associated with diabetes after kidney transplant in patients on tacrolimus
Robarts Research Institute - Study identifies novel stem cell in blood and vessel formation
Roche Pharmaceuticals - New hepatitis B indication filed for PEGASYS filed in U.S., E.U. and Switzerland
Royal Victoria Hospital, Belfast - Optimal settings for Diprifusor propofol delivery determined
Russian Academy of Medical Sciences - H. pylori typing methods compared
SCYNEXIS Inc. - U.S. National Institute on Drug Abuse awards contract to development company
Schwarzeck-Verlag, GmbH - Dendrite completes strategic acquisition of German company
Scripps Research Institute - Mouse model developed to evaluate of DNA minigene vaccines
Se-cure Pharmaceuticals Ltd. - Report finds Femarelle can safely and effectively relieve menopausal symptoms
Seoul National University - Cadalene extract exerts antioxidative effect on NNK-induced lung tumorigenesis
Sigma-Aldrich Corporation - Life science products company obtains CE Mark certification for E.U. sales
Signet Laboratories, Inc. - Drug company plans to develop sepsis and acute renal failure products
St. James University Hospital, Leeds - Sympathetic neural hyperactivity occurs after unstable angina and acute MI
St. Louis University - Status of live attenuated influenza virus vaccine in U.S. reported
State University of Campinas - Child-Pugh classification predicts survival better than MELD in liver transplant
Sterling Financial Investment Group, Inc. - Financial investment group hires senior biotech analyst
Sting-Free - Tech company's new insole composite can block plantar fasciitis heel pain
TechniScan, Inc. - Stephen Blum joins ultrasound company's board
Tenet Healthcare Corporation - Tenet sells hospital assets of Redding Medical Center to Hospital Partners
TheraQuest Biosciences - Entities invest in bioscience company's development of pain management drugs
Thermo Electron Corp. - DPC inks agreement for TCAutomation and Konelab
Trinity Partners - Data solutions group to provide services for biotechs and pharmaceuticals
Tufts University - More than half of hospitalized stroke patients likely treated against guidelines
U.S. Department of Agriculture - Real-time RT-PCR applied for quantitation of avian influenza virus
U.S. Food & Drug Administration - RNA interference protects against lethal influenza virus challenge
U.S. Food & Drug Administration - Tissue partitioning of endotoxin for pharmacokinetic modeling determined
U.S. National Institutes of Health - Astrocytes contribute to retroviral neuropathogenesis through MCP-1 generation
U.S. National Institutes of Health - Pediatric patients require higher dosages of i.v. voriconazole than adults
United Soybean Board - New research shows shift in opinion on obesity epidemic
Univ. of Illinois, Urbana-Champaign - Isolated soy protein shown to benefit type 2 diabetics
Univ. of Texas SW Medical Center - Lipodystrophies are rare disorders causing metabolic syndrome
Universidade Federal do Rio de Janeiro - Pressure-inactivated foot-and-mouth disease virus is vaccine candidate
University Children's Hospital, Heidelberg - Glucocorticoid receptor inactivation in hepatocytes leads to hypoglycemia
University College London - DNA immunization achieved with plasmids expressing hCG beta-chimeras
University Medical Center, Utrecht - Cryptococcal glucuronoxylomannan disrupts endothelial neutrophil rolling
University Medical Polyclinic, Bonn - Nck-interacting proteins identified in vascular smooth muscle cells
University of Barcelona - Immune recovery slows after 3 years HAART and reaches plateau after 4-5 years
University of Basel Hospital - Persistent apoptosis in HIV patients associated with poor recovery of CD4 cells
University of California, San Francisco - Heart disease and cardiovascular malformations can occur in utero
University of Cincinnati - Effect of ingested fat on satiety reviewed
University of College London - ESHAP regimen cytoreduces resistant myeloma patients
University of Essen, Germany - Combination anticlotting therapy increases risk of bleeding
University of Groningen Hospital - Short-term smoke exposure attenuates ovalbumin-induced airway inflammation
University of Hong Kong - One-step quantitative RT-PCR assay detects SARS coronavirus
University of Hong Kong - Pathogenic role suggested for eukaryotic initiation factor oncogene
University of Ljubljana - Researchers develop an improved, automated 24-hour electrocardiogram device
University of Medicine, Berlin - Viruses may trigger heart disease, which can be followed by cardiomyopathy
University of Michigan - Endothelial nitric oxide synthase is protective in mice
University of Nebraska - Efficacy of external cardioversion waveforms compared
University of Regensburg - FasL-overexpressing dendritic cells purge activated T cells
University of Rotterdam - Barrett neuroendocrine cells have prognostic value in GEJ adenocarcinoma
University of Saarland - Antigenic peptide derived from cancer-testis antigen NY-ESO-1
University of Siena - Flk-1 target gene identities could elucidate vasculo-, angiogenesis pathways
University of Tokyo - Microfluidic PDMS bioreactor developed for large-scale culture of hepatocytes
University of Utrecht - Novel peptides inhibit SARS coronavirus
University of Washington - Gene therapy reaches muscles throughout the body and reverses MD in animal model
University of Washington - UW to lead most comprehensive study of air pollution and cardiovascular disease
Vanderbilt University - Nuclear import inhibition counters staphylococcal enterotoxin B
Varian Medical Systems - New treatment planning tools added to Eclipse radiotherapy software
Velcura Therapeutics, Inc. - Development of new DNA microarray to help speed bone disease research announced
Vernalis, Ltd. - Severe headaches more likely to occur around menstruation
Vical Incorporated - Phase 1 clinical trial with bivalent anthrax vaccine initiated
Virginia Bioinformatics Institute - Proteomic research centers target bioterrorism agents
Vital Living Inc. - Nutrition-focused company introduces first organic nutrition bar
Waters Instruments, Inc. - Medical instrument company named to Fortune's Top 100 List
Weill Cornell Medical College - Discovery of gene may mean stem cells exist in heart
Whitehead Institute for Biomedical Research - High-performance DNA multilane microdevice system developed
Wyeth Pharmaceuticals - Agreement reached in national diet drug settlement
Yamanouchi Pharmaceutical Co. Ltd - Novel 5-HT2c receptor agonist possesses anti-obesity activity
Yellowstone Neurosurgical Associates - Getting relief from pain can be shocking
Yonsei University, Seoul - Estrogen receptor associated with epithelioid variants of renal angiomyolipoma
York University - Protein expression profiling malignancies reveals new tumor marker
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