Published in Pharma Law Weekly, August 17th, 2004
According to published research from the United States, "Alveolar macrophages (AM) represent important effector cells in the innate immune response to the AIDS-related pathogen Pneumocystis, but the early AM host defense signaling events are poorly defined."
"Using AM from healthy individuals," J.M. Zhang and colleagues reported, "we showed in the present study that Pneumocystis organisms stimulate AM NF-kappaB p50 and p65 nuclear translocation in a time-dependent and multiplicity-of-infection-dependent manner as determined by electrophoretic mobility...
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