Published in Pharma Law Weekly, October 5th, 2004
"It has been suggested that urokinase plasminogen activator (uPA) in cancer cells is upregulated by the p185 kD form of the HER-2/neu oncogene," said obstetrician/gynecologists at Long Island Jewish Medical Center, New York.
D.N. Contreras and colleagues investigated whether "the extracellular domain of HER-2/neu, the p105 fraction, which is found in the circulation, has any regulatory influence on uPA in patients with cervical cancer."
According to their...
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