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Stanford University

Strain from low aortic wall velocities in vivo can be quantified in vivo

Published in Pharma Law Weekly, October 12th, 2004

Porcine study shows that the thoracic aorta does not deform uniformly under strain.

According to a study from the United States, "Artery wall motion and strain play important roles in vascular remodeling and may be important in the pathogenesis of vascular disease. In vivo observations of circumferentially nonuniform wall motion in the human aorta suggest that nonuniform strain may contribute to the localization of vascular pathology."

"A velocity-based method to investigate circumferential strain variations was previously developed and validated in vitro; the current study was undertaken to determine whether accurate displacement and strain fields...

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