Pharma Law Weekly
Susan Hasty, Publisher
Table of Contents . . . January 4th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Pharma Law Weekly | Other Publications
AARP - New York attorney general enlists seniors to monitor drug prices
Belcher Pharmaceuticals, Inc. - GeoPharma reports levothyroxine-related patent
CHF Technologies, Inc. - Chase Medical files patent infringement suit
CMS Media Affairs - Medicare Modernization Act already helping millions in first year
Celgene Corporation - Patents licensed to isotretinoin manufacturers for safe distribution
GenoMed, Inc. - Company's treatment for prion diseases including mad cow disease to be tested
Ginacor, Inc. - U.S. FDA approves HealthStep bathroom device
Healthcare Coverage - Humana to introduce New Medicare Advantage PPO plan to Kansas City area seniors
InfaCare Pharmaceutical Corporation - Stanate hyperbilirubinemia treatment awarded novel process patent
Information Technology - Cedara introduces software that tracks patient information
Laboratory Corp. of America Holdings - Chiron inks agreement for hepatitis C plasma testing
Legal Issues - Investor Icahn sues Mylan, Perry alleging vote buying
Medical Discoveries, Inc. - Biotechnology company announced equity private placement
Odyssey Thera, Inc. - Biopharma company issued patent for PCA technology
Pediatric Care - Alliance announced to identify, treat methamphetamine-exposed children
AARP - Study finds prescription drug cost increases outpace inflation
ALTANA, AG - European marketing for Alvesco to begin
AMDL, Inc. - Diagnostics company announces first closing of private offering
Abbott Laboratories - Novel HIV integrase inhibitors block strand transfer into host DNA
Adenosine Therapeutics, LLC - NIH grant awarded to develop drug eluting stent to prevent restenosis
Alliance Imaging, Inc. - Imaging services firm announces tender offer
American College Health Association - Survey shows increase of depression among college students
American Psychological Association - CIGNA settlement favorable to psychologists
American Society of Hematology - Researchers unlock understanding to Streptococci infection
American Society of Hematology - Studies presented at conference offer promise for sickle cell disease treatment
AngioDynamics, Inc. - Insurance coverage of laser therapy for varicose veins added
Ankara University - Viral heterogeneity is uncommon in Turkish patients with hepatitis infections
Antares Pharma - Results from needle-free human growth hormone trial presented
Applera Corp. - Dennis Gilbert, PhD, elected as CSO, VP for research of Applied Biosystems
Arena Pharmaceuticals, Inc. - Anti-obesity compound well tolerated in phase Ib trial
Aristotelean University of Thessaloniki - Statin + ACE inhibitor combination is more effective than either treatment alone
Astralis, Ltd. - Psoriasis drug maker reports loss of $0.02 per share
Auburn University - Diabetes affects astrocyte glial fibrillary acidic protein in CNS
Bayer Biological Products - Sterile filling facility receives additional regulatory approvals
Becton, Dickinson and Company - Companies enter agreement to introduce auto-disable syringes in India
Boston Scientific Corporation - Codes reported for intravascular ultrasound procedures
Bracco Diagnostics, Inc. - Contrast agent for central nervous system gets FDA approval
Brown Medical School - Families inform roadmap to improve care for dying in nursing homes
Buffalo General Hospital - Small and large colon tumors respond differently to CpG oligonucleotides
Business Update - Chronimed/Aetna extend specialty-pharmacy distribution contract
CHU Amiens - Several large-scale trials are investigating statin use in kidney patients
CHU Vaudois, Lausanne - Papers emphasize embryo cryopreservation in defining standard of ART success
CSI Beverages - Treated water helps diabetics hydrate better
Cambridge Institute for Medical Research - Mutation affecting TrkB linked to severe obesity
Canadian Brain Tumour Consortium - Canadian tumor group actively researching promising drugs
Cancer Nursing - Two methods found effective in educating Iranian women about cervical cancer
Cardiff University - Genetic screening follow-up, policies lacking
Cardiff University - Vector toxicity confounds herpes simplex virus-mediated gene delivery
Cardiome Pharma Corp. - Cardiome selects oral RSD1235 formulation
Case Western Reserve University - Demineralized cortical bone matrix repairs osteochondral defect
Case Western Reserve University - Researchers discover naturally occurring COX-2 inhibitor
Catholic Research Inst. of Medical Sciences - A novel SCN5A gene mutation correlates with Brugada syndrome in Koreans
Catholic University of Korea - Epicatechin inhibits nitric oxide synthase expression in pancreatic islets
Center Hopital Cayenne - C. neoformans-related meningitis reported in AIDS patients in French Guiana
Charite Univ. of Medicine, Berlin - Renin angiotensin system inhibitors may benefit postmenopausal women
Charles River Laboratories International - Pharmaceutical company names new president of global preclinical services
Chinese Ministry of Science and Technology - SARS vaccine primarily proved safe and effective
Chiron Vaccines - Progress and challenges in infectious diseases reviewed
Cincinnati Children's Hospital - Diagnosing inner ear hearing loss now less invasive with genetic testing
Collagen Matrix, Inc. - U.S. FDA clears DuraMatrix Collagen Dura Substitute Membrane
ConvaTec - Company launches advanced fecal incontinence management system
Cranberry Institute - Cranberries may help prevent breast cancer
CuraGen Corporation - Single dose phase 1 data on drug to prevent oral mucositis presented at ASH
Cutting Edge Information - Big pharma incorporates competitive intelligence at a rate of 87%
Cyberkinetics Neurotechnology Systems - Spaulding Rehabilitation joins BrainGate Neural Interface System pilot study
CytRx Corp. - Data shows potential of arimoclomol to reverse nerve degeneration
DEY, L.P. - Symposium offers guidance on COPD best clinical practices
Dartmouth College - UBE1L is a candidate target for chemoprevention
Datascope Corp. - Company acquires manufacturing rights to anesthesia-delivery products
Decision Resources, Inc. - Investor consultant forecasts oral lung cancer drug sales to reach $103 million
Dongguk University - Herbal mixture inhibits platelet aggregation
Dr. Reddy's Laboratories Ltd. - Pharmacokinetics of ragaglitazar determined in rats
Drug Utilization - Consumer magazine issues ratings for drugs
Duke University, North Carolina - Deep vein thrombosis and pulmonary embolism are often clinically unsuspected
EMMES Corporation - Predictors of transplant outcome in pediatric FHF patients identified
East Carolina University - G-beta-gamma subunits regulate two ion channels with different functions
Express Scripts - Generic drug use varies widely by state, study reveals
Fred Hutchinson Cancer Research Center - The 29th annual Hutch Holiday Gala raises more than $4.88 million
Fujisawa Pharmaceutical Co. - Microfluidic immunoassay facilitates tacrolimus monitoring
GenVec, Inc. - Company expands PEDF rights for all ocular diseases from NIH
Genmab, A/S - Encouraging efficacy data reported from HuMax-EGFr trial in head and neck cancer
GlaxoSmithKline - HHS purchases 1.2 million doses of flu vaccine
GlaxoSmithKline - Membrane permeability of abacavir consistent with its ability to penetrate CNS
Glostrup University - Cardiovascular risk increased with low albuminuria in diabetic patients
Greystone Associates - Report: Combination-product share of drug-delivery market to approach $40B
HTS Biosystems - Dyax enters collaboration agreement
Harvard Health Publications - Harvard Health Publications lists top 10 health stories for 2004
Harvard University - Cell transmigration induced by Pseudomonas requires hepoxilin A3
Harvard University - Novel phenyltropane derivatives show promise as PET imaging agents
Harvard University - Proteinuria as biomarker of progressive kidney disease investigated
HealthAmerica and HealthAssurance - Managed care company named president and CEO
Henri Poincare University - Polyclonal antibodies used as tool for proteomics research
Home Safety Council - National Falls Prevention summit convened in Washington, DC
Hopital Lariboisiere, Paris - AMM may develop partial neuroprotective function in long-lasting prion diseases
ICOS Corporation - Biotechnology company announces new board of directors appointment
ID Biomedical Corporation - Biotechnology company to ship 1.2M doses of flu vaccine to Canadian market
IMCOR Pharmaceutical Co. - Phase II study to investigate alternative methods of administration for Imagent
IMPAX Laboratories, Inc. - FDA approves ANDA for generic version of Wellbutrin SR 200mg Tablets
INSERM U525, Nancy - Factor VII gene may be a susceptibility locus for hypertension
Imaging Dynamics Company - SourceOne signs U.S. distribution agreement for Xplorer Digital Radiography
Immune Response Corporation - Immunology-focused company announces expansion of multiple sclerosis program
InKine Pharmaceutical Company, Inc. - Pharmaceutical company to return Colirest patent license to the licensor
Indian Veterinary Research Institute - ELISA developed to diagnose Peste des petits ruminants infection
Indiana University - Lilly Endowment gives Indiana University $53 million for life sciences
Indigent Healthcare - King County, Washington, finds average homeless person dies at age 47
Influenza Vaccine - Washington still has plenty of flu vaccine for high-priority kids
Initiate Systems - Software and services company selected by Northeast Georgia Health System
Institute Diabetes Discovery LLC - Inhibitors of aldose reductase to treat diabetic complications synthesized
Institute for OneWorld Health - Effort could significantly reduce cost, boost supplies of artemisinin
Institute of Child Health, London - Gene therapy for severe combined immunodeficiency shows promise
International College of Surgeons - British surgeon assumes world presidency of International College of Surgeons
Introgen Therapeutics, Inc. - Biopharmaceutical company announces $16 million financing
John Wayne Cancer Institute - Polyvalent prostate cancer vaccine developed
Kagoshima University - Leptin directly modulates cell proliferation and apoptosis of osteoblasts
Kaiser Permanente - Physical activity helps prevent increased weight in women at midlife
Karolinska Institute - Antigen-specific T-cell functions are suppressed over estrogen-DC-IDO axis
Karolinska Institute - Histone deacetylase inhibitor 4-phenylbutyrate augments suicide gene therapy
Khon Kaen University - PCR used to diagnosis P. carinii from sputum and bronchoalveolar lavage samples
Kitano Hospital - Guanylyl cyclase pathway not involved in inhibition of HIF-1 activation
Konkuk University - Red yeast rice extracts suppress adipogenesis
Kyoto Prefectural University of Medicine - Exercise affects hepatic gene expression in rats
L'Hopital Lariboisiere Fernand Widal, Paris - Study looks at epidemiology of pain in depression
LodgeNet Entertainment Corporation - Alabama hospital launches interactive television, access system in patient rooms
Lung Cancer - Vitamin E in plant seeds could halt prostate, lung cancer
Maxygen, Inc. - Pharma company terminates development of interferon beta program
Mayo Clinic - Loss of bone density seen with inhaled corticosteroids
Mayo Clinic Foundation - Dopamine release and uptake analyzed, effects of neurotensin analog revealed
McKesson Medical-Surgical Inc. - Healthcare services company signs distribution, purchasing agreements
McMaster University - Toll-like receptor 3 agonist protects against genital herpes
MedValue - Claims processing company hosts roundtable discussion
Medex, Inc. - Medical products manufacture to be acquired by Smiths Group
Medical Center Rijnmond Zuid, Rotterdam - Procalcitonin is an early marker of bacterial disease in neonates and children
Medical College of Ohio - Actions of aldosterone and spironolactone are caused by different mechanisms
Medical College of Wisconsin - Adult skin could provide alternative to embryonic stem cells
Medical College of Wisconsin - L-arginine transport crucial for renal medulla blood flow and NO production
Medical University of South Carolina - Doctors urge wider detection and treatment of sexually transmitted disease
Medical University of South Carolina - Presentation of type 2 diabetes in older adults described
Merck Frosst Center for Therapeutic Research - Yeast used to screen for inhibitors of protein tyrosine phosphatase 1B
Millipore Corporation - Biosciences company names new president and CEO
Monash University - Oxidative stress analyzed, counter-regulation revealed
Mt. Sinai School of Medicine, New York - Interferon promoter activation studied, termini of influenza B virus required
NOP World - Index offers perspective on health and fitness values, attitudes and behaviors
Nanogen, Inc. - Patent issued for active biological sample preparation apparatus
Nara Women's University - The novel membrane protein Neuro-p24 is essential for neurite extension
National Cardiovascular Center, Japan - Study explores the function of autosomal recessive hypercholesterolemia protein
National Institute Animal Health, Tsukuba - Three major genetic groups associated with recent IB outbreaks in Japan
Natl. Inst. for Environmental Studies, Ibaraki - Effects of diesel exhaust on LPS-related gene expression characterized
Neurochem Inc. - Completion of phase II/III clinical trial for Fibrillex announced
New York University - Molecular mechanisms of fear conditioning in lateral amygdala reviewed
NitroMed - Pharma company prices public offering of common stock
Northwestern University - Combined CABG and orthotopic liver transplantation feasible
Northwestern University - PPARgamma ligands help the thrombospondin peptide ABT510 fight tumor growth
Norwood Abbey Limited - Ophthalmic devices company expands distribution to five countries
Nottingham University - T helper cell responsiveness predicts susceptibility to nematodes in humans
Ohio State University - New pathway identified in angiogenesis
Oregon Health & Science University - Heightened osmolality raises excitatory amino acid drive in rat RVLM
Orthofix International, N.V. - Medical device company announces appointment of new directors
PSS World Medical, Inc. - Vaccine company commented on influenza vaccine supply and distribution
PTC Therapeutics, Inc. - Biopharma company announces orphan drug designation for PTC124
Par Pharmaceutical Companies, Inc. - Pharma company announces investment, shipment of generic K-Dur
Pasteur Institute, Antananarivo - Artemether-lumefantrine effective against resistant P. falciparum
Pediatric Obesity - Childhood obesity crisis poses financial losses to schools
Pediatrix Medical Group, Inc. - Newborn and maternal fetal physician services provider announces acquisition
Pennington Biomedical Research Center - Metabolic approach to obesity pathogenesis presented
People's Hospital Hainan Province - Triptolide appears to be a moderately effective immunosuppressive
Pfizer Inc. - Long-term data show benefit of Detrol LA as first-line therapy
Phenomix Corporation - Pharma partnership results in inflammation drug candidate
Policlinico San Matteo, Pavia - Nested PCR sensitive/specific for diagnosis of visceral leishmaniasis from PBMC
Prolysis Ltd - Drug discovery companies partner on antibiotics program
Prostate Cancer - Abbott applies for approval of prostate cancer drug
Provectus Pharmaceuticals, Inc. - Pharma company announced private placement transaction
Proxima Therapeutics - Australia and New Zealand MammoSite distributor announced
Queensland University of Technology - Mouse models of obesity reviewed
Quintiles Transnational Corp. - Poster presented showed results of asthma assessment program
RWTH University of Aachen - IL-11 signaling is important in regulation of trophoblast invasion
Renovis, Inc. - Ischemic stroke phase III enrollment completed
Robert Wood Johnson Medical School, Piscataway - Regulation of p53 activity analyzed, lysine methylation revealed
Roche - New drug application submitted to FDA for intravenous injection of Boniva
Royal Melbourne Institute Technology - Suppression of free fatty acids upregulates PPAR-alpha and -delta
Rutgers University - Glutamate receptor export analyzed, regulation by unfolded protein revealed
Rx for Ohio - Free program helps Ohioans find information on free or discounted medicines
RxGen, Inc. - Biotech firm gets NIH grant to study environmental causes of Parkinson disease
SARS - U.S. government launching human trials of experimental SARS vaccine
SUNY Stony Brook - Galanin studied, no effect on selected operant parameters revealed
Salk Institute for Biological Studies - Hormone release from hypothalamus explants analyzed, interactions revealed
Sangamo BioSciences, Inc. - World Economic Forum selects 20 Technology Pioneers for 2005
Sanguine Corporation - Robert Kwun joins medical advisory board of synthetic red blood cell developer
Sapporo Medical University - Occludin immunostaining may have diagnostic value
Schering Plough Research Institute - Desloratadine plus fluoxetine caused no significant changes
SeraCare Life Sciences, Inc - Life sciences company, Cellular Technology partner on immune reactivity testing
Sirna Therapeutics, Inc. - Hair removal company launches dermatology division to target gene technology
Somnia, Inc. - Anesthesia services provider names Jamie Harris government relations director
Southern Illinois University, Carbondale - Approach provides clinical training that directly integrates with basic science
St. Louis University, Missouri - Central neuropeptide activates stress hormone secretion and stimulates feeding
Stanford University Medical Center - California university blood center gives special T-shirt for blood donation
State University of New York, Stony Brook - DNA repair enzyme OGG1 plays role in cell cycle regulation
Stressgen Biotechnologies - Enrollment completed for clinical trial of internal genital warts treatment
Sumitomo Chemical Co. Ltd. - Alpha2 -macroglobulin marks obscure hepatocellular (pre)neoplastic lesions
Sungkyunkwan University - Death effectors of beta-cell apoptosis in type 1 diabetes reviewed
Sygen International, plc - Genaissance Pharmaceuticals signs research agreement
Symmetry Medical Inc. - Orthopedic implant, devices provider prices initial public offering
Synergos, Inc. - Endovasc outlines plans for continued development of Liprostin, hires CRO
Synovis Life Technologies, Inc. - Technology company purchases rights to microsurgery bioabsorbable nerve conduit
TOPGEN - First clinical trial for new inhalation drug to treat asthma to be tested
Targacept, Inc. - Biopharmaceutical company with CNS-focus raises $33 million in private placement
Technical University of Dresden - High-density DNA microarray dissects pancreatic carcinoma gene expression
The Children's Hospital of Philadelphia - Study shows newborns with congenital heart disease have low brain blood flow
Thoratic Corporation - Implant-focused company updates Q4 sales, implant activity through November 2004
Toshiba America Medical Systems - 64-slice CT cardiac scanner installed at Nevada diagnostic imaging center
TransMolecular, Inc. - Clinical trial with amino acid peptide conjugate to treat glioma completed
Triad Therapeutics - Company reports sale of p38 kinase inflammation inhibitor program to Novartis
Tutogen medical, Inc. - Biological implant company reports year-end financial results
U.S. Centers for Disease Control and Prevention - Married adults are the healthiest, new CDC report shows
U.S. Dept. of Health and Human Services - U.S. HHS secretary announces plan to fight diabetes, promotes prevention
U.S. Food & Drug Administration - Accelerated approval of oncology products in U.S. reviewed
U.S. National Institutes of Health - Cytochrome c inserts into the bilayer and resides in its hydrophobic core
U.S. National Institutes of Health - Mapping of human genetic variation will speed search for disease genes
U.S. National Institutes of Health - Noninvasive images assess Kaposi sarcoma vascularity and treatment response
UCB Pharma, Inc. - Keppra Pregnancy Registry launched to monitor drug's impact on epileptic women
UnitedHealth Group - Discount drug care gives discounts to Medicare beneficiaries
Univ. of California - San Francisco - Brain can be trained to process sound in alternate way
Univ. of California, Berkeley - Serine repeat antigen gene family phylogeny in Plasmodium investigated
Univ. of California, San Francisco - Inadequate sleep in late pregnancy may influence labor and delivery
Univ. of Illinois, Urbana-Champaign - Selective coatings create biological sensors from carbon nanotubes
Univ. of Texas SW Medical Center - Pegylated interferon used for hepatitis C in interferon nonresponders
Universidad Nacional Autonoma de Mexico - Mimotopes of conformational epitopes in fibrillar beta-amyloid identified
Universite Laval, Quebec City - Little evidence found that diagnosis leads to employment discrimination
University Clinic, Munster - Right ventricular arrhythmias require detailed diagnostic evaluation
University College London - Cannabinoid-mediated neuroprotection results from interferon-gamma treatment
University College London - Pacemakers could protect patients with epilepsy from sudden unexplained death
University College London - Study examined effects of cyclophilin-D on permeability transition
University of Alabama - Subfascial augmentation mammaplasty avoids side effects of subpectoral approach
University of Antwerp - Electroporation aids RNA-based gene transfer to adult stem cells and T cells
University of Basel - Lamin A mutations have been associated with human laminopathies
University of Bordeaux - Pilot program targets mother-to-child HIV transmission in rural Zimbabwe
University of Bristol - HLA transgenic mouse provides insights on autoimmune diabetes
University of California San Francisco - Amyloidosis seen in mice expressing human amyloid peptides with Arctic mutation
University of California, Davis - Cassette-based digital mammography an alternative to screen-film mammography
University of California, San Diego - Hyperosmotic-hyperviscous small volume resuscitation safe and effective
University of California, San Diego - Remote memory access similar in HIV-associated dementia and Huntington disease
University of Cologne - Angiogenesis accompanies myelofibrosis in chronic myeloproliferative disorders
University of Fed Rio de Janeiro - Diterpenes isolated from marine alga active against HIV-1 RT
University of Glasgow - Scientists reveal the dangers of counterfeit cigarettes
University of Helsinki - CXCL12/IL-2/IL-6/IL-7/IL-15 inhibits spontaneous CD45R0+ CD4+ T cell apoptosis
University of Iowa - Neisseria gonorrhoeae's mechanisms of infection differ between sexes
University of Iowa - Methods detecting exposure to biological agents are ripe for development
University of Iowa - TRPV1 function in sensory neurons enhanced by specific receptor activation
University of Iowa - cAMP, serum, glucocorticoid-inducible kinase regulate epithelial Na+ channel
University of Istanbul - Maintaining sinus rhythm was beneficial for patients with atrial fibrillation
University of Klinikum Munster - sfpA gene is a screening target for sorbitol-fermenting E. coli O157:H-
University of Laval - Peripherin gene deletion is linked to amyotrophic lateral sclerosis
University of Medicine & Dentistry, New Jersey - BDI-FS is useful for assessing mood disorders in HIV patients with chronic pain
University of Melbourne - Human Activity Profile better measure in women than in men
University of Melbourne - Neurite outgrowth regulated by suppression of signaling and growth factors
University of Melbourne - Normal baroreceptor-HR reflex prevails in the presence of natriuretic peptides
University of Messina - Raxofelast reduces testicular ischemia-reperfusion injury
University of Minnesota - Early onset of risk factors accounts for high CV mortality in renal patients
University of Montpellier, France - More centenarians in Switzerland than any other European country
University of Munich - Mitogen-activated protein kinase cascade studied, opiod receptors involved
University of Munster - Low inhibitor concentrations increase the risk of symptomatic thromboembolism
University of Nebraska - Data demonstrate radical stress in autonomic areas of the brain in heart failure
University of North Carolina - Multiple V1/V2 env variants frequently present during primary HIV infection
University of North Carolina - Suicide rate possibly linked to chemicals released from asphalt plants
University of Pennsylvania - Transcriptionally restricted genes can be activated in unrelated tissues
University of Perugia - CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86
University of Pittsburgh - Diminished complexity of EEG time series during sleep may underlie impairments
University of Pittsburgh - Lymphoid depletion and immunosuppression weaning extend liver graft survival
University of Rochester - Expression of inflammatory chemokines analyzed, fibrinogen regulation revealed
University of Rostock - Novel hybrid heart valve scaffold developed for tissue engineering
University of Santiago Compostela - Unique/specific clone related to Vibrio parahaemolyticus outbreak in Europe
University of Southampton - Acupuncture - no longer a pain in the neck
University of Sydney - Platinum(IV) complex activity studied in ovarian cancer cell lines
University of Tennessee - Tyrosine phosphorylated villin analyzed, role in cell motility revealed
University of Toronto - Novel microarray detects microRNA expression
University of Tuebingen - Prospective targets for staphylococci drugs and vaccines reviewed
University of Utrecht - Novel typing scheme studies genetic relatedness/epidemiology of E. faecium
University of York - New study reveals that manipulation and exercise can help back pain sufferers
University of the State of Rio de Janeiro - Effect of unilateral nephrectomy on renal function of diabetic rats studied
Uppsala University Hospital - Bariatric surgery reviewed
Vertex Phamaceuticals - Biotech company names Kerry Reinerstsen VP, corporate, business development
Vi-Jon Laboratories - Schools from daycare to college use hand sanitizers to fight the flu bug
Virginia Tech - Quinoline compounds stimulate cell differentiation in breast tumor cells
Vrije University Medical Center, Amsterdam - Utility of microarray-based comparative genomic hybridization reviewed
Washington State University - Follicle-stimulating hormone provokes genetic changes in the murine testis
World Health Organization - Health actions for children in Togo to save thousands of lives in record time
Z-KAT Inc. - Florida company recognized by World Economic Forum as Technology Pioneer 2005
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