Hospital dos de Mayo, Lima
Metronidazole/nystatin ovules more effective than gel formulation against BV
Published in Pharma Law Weekly, February 1st, 2005
S. Sanchez and colleagues at the Hospital dos de Mayo in Lima wrote, "We compared metronidazole 0.75% gel (containing 37.5 mg metronidazole per dose) with ovules containing metronidazole 500 mg and nystatin 100,000 U, for intravaginal treatment of bacterial vaginosis (BV).
"In a single-blinded trial, symptomatic women with BV by both Amsel and Nugent criteria were randomly assigned to gel or ovules, once nightly for 5 nights, and asked to return three times after treatment. Analyses were intent-to-treat."
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Source: Pharma Law Weekly (2005-02-01)
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