Published in Pharma Law Weekly, April 26th, 2005
"Gherlin, the endogenous ligand for the GH secretagogue receptor (GHS-R), is a recently isolated hormone, prevalently expressed in stomach but also in other tissues such as hypothalamus and placenta. This novel acylated peptide acts at a central level to stimulate GH secretion and, notably, to regulate food intake. However, the existence of further, as yet unknown, effects or presence of ghrelin in peripheral tissues cannot be ruled out," wrote J.E. Caminos and colleagues, University Santiago Clinical Hospital.
"In this report, we provide clear evidence...
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