Published in Pharma Law Weekly, July 26th, 2005
"Judging from anti-TLR mAb/inhibitor-blocking analysis, MDP derivatives with a single octanoyl or stearoyl fatty acid chain were found to activate TLR2 and TLR4 on human DCs, although intact and diacylated MDP expressed no ability to activate TLRs," scientists writing in the Journal of Immunology report.
"Human DC activation profiles by the monoacylated MDP were essentially similar to those by...
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