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EORTC Data Center, Brussels

Bacillus Calmette-Guerin compared against chemotherapy for bladder cancer

Published in Pharma Law Weekly, August 16th, 2005

Bacillus Calmette-Guerin (CCG) was compared against intravesical chemotherapy for the treatment of bladder cancer.

"We determined the short-term and long-term efficacy of BCG and chemotherapy in the treatment of patients with carcinoma in situ (CIS). A meta-analysis was performed on published results of randomized clinical trials comparing intravesical BCG to intravesical chemotherapy. Nine randomized trials including 700 patients with CIS compared BCG to either mitomycin C (MMC), epirubicin, adriamycin, or sequential MMC/adriamycin," scientists writing in the Journal of Urology reported.

"Of 298 patients on BCG, 203 (68.1%) had a complete...

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