Published in Pharma Law Weekly, September 27th, 2005
According to recent research from United Kingdom, "In some bacteria, salicylate is synthesized using the enzymes isochorismate synthase and isochorismate pyruvate lyase. In contrast, gene inactivation and complementation experiments with Yersinia enterocolitica suggest the synthesis of salicylate in the biosynthesis of the siderophore yersiniabactin involves a single protein, Irp9, which converts chorismate directly into salicylate."
"In the present study, Irp9 was for the first time heterologously expressed in Escherichia coli as...
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