University of Tokyo

Musculin/MyoR expressed in kidney side population cells/regulates their function

Published in Pharma Law Weekly, October 4th, 2005

Musculin/MyoR is expressed in kidney side population cells and regulates their function.

"Musculin/MyoR is a new member of basic helix-loop-helix transcription factors, and its expression is limited to skeletal muscle precursors. Here, we report that musculin/MyoR is expressed in adult kidney side population (SP) cells and can regulate their function," scientists writing in the Journal of Cell Biology report.

"SP phenotype can be used to purify stem cell-rich fractions. Microarray analysis clarified that musculin/MyoR was exclusively expressed in kidney SP cells, and the cells resided in the renal interstitial space.

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Source: Pharma Law Weekly (2005-10-04)

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