U.S. National Institutes of Health
Targeting the Env lipid domain inactivates HIV and SIV
Published in Pharma Law Weekly, November 22nd, 2005
According to a study from the United States, "We describe a new approach for the preparation of inactivated retroviruses for vaccine application. The lipid domain of the viral envelope was selectively targeted to inactivate proteins and lipids therein and block fusion of the virus with the target cell membrane.
"In this way, complete elimination of the infectivity of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) could be achieved with preservation of antigenic determinants on the surface of the viral envelope."
Y. Raviv and colleagues at the U.S....
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Source: Pharma Law Weekly (2005-11-22)
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