University of Valme Hospital, Seville

Transient viremia associated with emergence of HAART-related drug resistance mutations

Published in Pharma Law Weekly, January 17th, 2006

Transient rebounds of HIV viremia are associated with the emergence of HAART-related drug resistance mutations.

According to a study from Spain, "There are very few and contradictory data about the consequences of 'blips', transient rebounds of HIV viremia. We assessed the emergence of new drug resistance mutations during blips among HIV-infected patients on HAART from a cohort in which we found no association between blips and virological failure."

"Seventeen patients with blips were selected from 330 patients under HAART for over 48 weeks according to these criteria: (1) presence of only one blip, viremia {{<=}}1000 copies/mL preceded by two...

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Source: Pharma Law Weekly (2006-01-17)

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