Pharma Law Weekly

National Center in HIV Epidemiology & Clinical Research, Sydney - Increased IL-7 correlates with decreased CD127 and increased CD132 expression in HIV/AIDS

National Taiwan University Hospital - Reports advance knowledge in SARS research

Neurochem Ltd. - Neurochem submits new drug application to U.S. FDA for Fibrillex for Amyloid A (AA) amyloidosis

Niigata University - Recent findings in cardiology described

Northeastern University, Boston - Darbepoetin alfa saves costs and reduces number of office visits for treatment-related anemia

Ohio State University - Chronic lymphocytic leukemia linked to CpG island methylation

Ohio State University - Clinical utility of standardized uptake value on FDG-PET in colorectal cancer assessed

Ohio State University - Ovarian cancer inhibited by 9-methoxy-2-methylellipticinium acetate

Okayama University of Science - Models for simulation of signaling network aid in silico evaluation of drug candidates

Onyvax Ltd. - Transfection with cytokine may have limited long-term effectiveness

Oral Health - Pharmacologist receives 510(k) clearance to market Sucralfate HCl Topical Paste for oral lesions

Oregon Health & Science University - Methamphetamine and dopamine differentially affect transporter-mediated efflux

Oregon State University -  Mycobacterium avium genes associated with biofilm formation

Ortho Women's Health & Urology - Ortho Evra study shows risk of VTE and DVT similar to oral contraceptives

Osaka City University - A biodegradable polymer functions as a carrier material

Otto von Guericke University, Magdeburg -  H. pylori reduces secretory leukocyte protease inhibitor levels in gastroduodenal mucosa

Ovarian Cancer - Ovarian cancer treated by abraxane

PRA International - PRA International announces increase in net income of 55%

Pain Management - Once daily Ultram ER tablets now available in the United States

Panacos Pharmaceuticals, Inc. - Panacos reports net loss of $8.3 million or $0.17 per share

Pasteur Institute , Paris - Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells

Pathogen Removal and Diagnostic Technologies, Inc. - Blood-borne infectivity study shows dramatic reduction in TSE prions

Pennsylvania Department of Health - Anthrax case identified in Pennsylvania

Polish Academy of Science - Two novel, small-molecule inhibitors of DNA methylation discovered

Possis Medical, Inc. - AngioJet therapy safe, effective as part of rescue percutaneous coronary interventions

Princess Margaret Hospital, Toronto - Studies add new findings to prostate cancer body of knowledge

ProBioGen - ProBioGen, Affimed continue clinical materials collaboration

Progenics Pharmaceuticals, Inc. - Progenics Pharmaceuticals HIV drug, PRO 140, receives U.S. FDA fast-track designation

Purdue University, West Lafayette - Polymer-coated targeted drug delivery systems stochastically modeled

QuatRx Pharmaceuticals Company - QuatRx Pharmaceuticals Company initiates phase II trial of fispemifene for andropause

Queen's University of Belfast - Proteins governing angiogenesis and bone growth interact during osteoclastogenesis

Research Australia - Grants put Australian National University in avian flu fight frontline

Rexahn Pharmaceuticals - Rexahn and University of Maryland Nanomedicine Center to develop cancer and CNS therapies

Rikshospitalet University Hospital, Oslo - Findings advance knowledge in surgical technology research

Roche - Roche pursues European market approval of Herceptin for early-stage HER2-positive breast cancer

Rosetta Genomics Ltd. - Research collaboration to develop micro-RNA related therapies for liver cancer announced

Roswell Park Cancer Institute, Buffalo - Dendritic cells are regulated by physiologically relevant thermal stress

Royal Cornwall Hospital, Truro - Studies describe new findings in cervical cancer screening research

Rush University Medical Center, Chicago - Researchers provide details of new studies and findings in the area of diagnostics

SRI Surgical Express, Inc. - SRI Surgical signs agreement to distribute implant tracking system to tissue banks

SUNY, Buffalo - IL-IM subunits within the IL-17R complex undergo conformational change upon ligand binding

Saitama Medical School - Decidual angiogenesis is driven by cytokine-stimulated fibroblasts

ScImage - Scimage announces single database web-based RIS/PACS solution

Scil Technology - First patient enrolled in phase 2 sinus lift study of bone augmentation product

Second University of Naples - Physiological, pathological ventricular hypertrophy is identifiable with combined 2D echo/Doppler imaging

Selcuk University, Konya - Valproate lowers glucose and raises insulin, cortisol, leptin, and neuropeptide Y levels

Senesco Technologies, Inc. - Senesco reports Q2 2006 net loss of 6 cents per share, compared to 5-cent loss a year ago

Seth Gordhandas Sunderdas Medical College, Mumbai - HIV infection probability in a child depends on nature/number of manifestations present

Slovak Academy of Sciences - Antidiabetic and sulphonyureas drug interactions with K_ATP channels discussed

Smiths Medical MD, Inc. - Smiths Medical MD to distribute medComp's Split Stream catheters for hemodialysis

Solexa, Inc. - Genome analysis system developer Solexa transfers listing to Nasdaq National Market

South Carolina Heart Center - In suspected coronary artery disease, 64-slice cardiovascular CT is a reliable diagnostic tool

Southampton General Hospital - Hepatic steatosis in obese subjects involves non-esterified fatty acids

St. Eriks Eye Hospital, Stockholm - Lower incidence of ARM reported in study of patients treated with high doses of antioxidants

St. Mary's Hospital, London - Metabolic syndrome is common following gestational diabetes in non-European women

Stanford University - New research in the area of statins detailed

Stanford University School of Medicine - Coronary intervention high-resolution real-time spiral MRI guidance promising

Statens Serum Institute, Copenhagen - Cancer risk among patients with multiple sclerosis assessed

Steno Diabetes Center, Gentofte - GNB3 825C >T polymorphism do not seem to be involved in metabolic syndrome

Sungkyunkwan University, Seoul - Gastric cancer may be suppressed by reversion-inducing-cysteine-rich protein with Kazal motifs

Syncro Medical Innovations, Inc. - Syncro Medical Innovations closes $2.2 million first round financing

Takeda Pharmaceutical Company Limited - Takeda wins patent infringement case against ANDAs for generic pioglitazone HCl

Tata Memorial Hospital, Maharashtra - Cytology of ileal conduit urine bladder cancer studied

The American Fertility Association - American Fertility Association releases U.S. HHS-funded brochures on embryo donation

The San Raffaele Hospital, Milan - Drug-eluting stents for ostial de novo left anterior descending lesions show decreased restenosis

Thermage, Inc. - Health Canada grants regulatory clearance for marketing of skin tightening system

Tohoku University, Sendai - LV hypertrophy in hypertensive patients may be predicted by peripheral radial augmentation index

Transition Therapeutics Inc. - U.S. patent granted to Transition Therapeutics for diabetes regenerative product

U.S. Centers for Disease Control & Prevention - Breast cancer screening should focus on older women

U.S. Centers for Disease Control & Prevention - Diarrhea in children is reduced by flocculant-disinfectant for drinking water

U.S. Centers for Disease Control & Prevention - Enterotoxigenic E. coli was cause of epidemic diarrhea

U.S. Centers for Disease Control & Prevention - Serum creatinine measurement improvement recommendations have been released

U.S. Food & Drug Administration - Studies describe new findings in smallpox vaccines research

U.S. National Institutes of Health - Colon cancer risk related to body mass index may be modified in women

U.S. National Institutes of Health - Human papillomavirus tissue affinity may contribute to carcinogenic potential

UITA - Utah IT and life science associations announce unanimous board agreement to merge

Uludag University, Bursa - In patients with myocardial infarction, N-acetylcysteine diminished oxidative stress, improved LV function

Universitatsklinikum Heidelberg - Wegener granulomatosis often diagnosed if destruction of the maxillary sinus' medial wall is found

Universitatsklinikum Tubingen - Lentigo maligna melanoma managed by three-dimensional histology

University Clinic Frankfurt - New findings in chemotherapy described

University College of London - Absence of Chx10 homeobox gene causes neural progenitors to persist in adult retina

University Hospital of Marques Valdecilla, Santander - Acute rejection episode may cause production of postrenal-transplant antiphospholipid antibodies

University Hospital of the Saarland - Monocyte adhesion is inhibited by 17-beta-estradiol via down-regulation of Rac1 GTPase

University Hospital, Lausanne - Hypertension is transient after surgical closure of an abdominal wall defect

University Hospitals of Leicester - Findings describe new data in myocardial infarction research

University at Buffalo - Chemical sensors detect diseases by analyzing human breath

University of Arizona - Rac1 maintains malignant phenotype of mouse skin tumor cells

University of Barcelona - Essential hypertension, urinary 12(S)-HETE are linked to coding polymorphism in 12-lipoxygenase gene

University of Birmingham - In coronary artery disease patients, acute stress influences thrombotic system differently

University of Bologna - Angiogenesis is modified by polychlorobiphenyl interactions with estrogen receptors

University of Bristol - New metabolic syndrome definitions modestly predict coronary heart disease risk in women

University of Bristol - Reports advance knowledge in surgical technology research

University of British Columbia - Nitric oxide reduces the microbial burden in healing wounds

University of California, San Francisco - Parenteral iron adverse reactions are focus of review

University of California, San Francisco - Recent findings illuminate research in cardiology

University of Cambridge - Choroidal neovascularization is amplified by a complement factor H variant and smoking

University of Catania - Exercise myocardial scintigraphy gives prognostic information concerning subsequent cardiac risk

University of Cincinnati - Vaccinia virus expressing IL-2 elicits immunity in head and neck cancer model

University of Copenhagen - Cellular delivery of nucleic acid conjugates is mediated by cationic lipids

University of Copenhagen - Referral of excised caruncular lesions for pathological examination recommended

University of Cordoba - Rapamycin-eluting stents for coronary bifurcation lesions underexpand without restenosis impact

University of Dundee - Antimonial compounds may work by disrupting thiol homeostasis

University of Essen - Impact of age on outcome in advanced ovarian cancer evaluated

University of Frankfurt - Findings in diagnostics provide new insights

University of Gottingen - New findings in the area of cancer therapy described

University of Helsinki - Thymosin beta 4 determines fibroblast transformation and invasiveness

University of Illinois - Americans prefer to leave child's sex to chance

University of Liverpool - HPLC-MS/MS simultaneously quantifies seven protease inhibitors in plasma

University of Liverpool Dental Hospital - Dental implant crevicular fluid pH assessed with modified touch electrode technique

University of Louvain - Researchers report details of new studies and findings in the area of cancer vaccines

University of Maryland - Sarcoplasmic reticulum Ca²⁺ efflux theory and practice are discussed

University of Maryland School of Medicine - Simple and accurate diagnostic tools monitor HIV infection

University of Michigan - Stressed-out women more likely to miscarry early

University of Milan - Interfractional patient setup variability in stereotactic radiotherapy reviewed

University of Minnesota - Crosstalk occurs between GTPases in mediating the effects of BDNF on retinal growth cone motility

University of Mississippi - Arg decarboxylase regulates agmatine in brain regions and neuronal cells

University of Montreal - Lopinavir/ritonavir and valproic acid interaction may exacerbate bipolar disorder

University of Montreal - Major cardiovascular event risk is directly related to degree of blood pressure lowering

University of Munich - Researchers detail new studies and findings in the area of diagnostics

University of Naples Federico II - Tissue factor expression in cultured endothelial and smooth muscle cells is induced by nicotine

University of Oslo - Rectal cancer patients receiving radiotherapy experienced reduced energy intake

University of Oxford - Antiviral CD8+ T cells may select hepatitis C virus escape mutants

University of Oxford - Hepatitis C virus ion channel p7 protein-protein interactions modeled

University of Paris 07 - Researchers describe findings in apoptosis studies

University of Parma - Prostate cancer prevented by oral administration of green tea catechins

University of Queensland - Recent findings in echocardiography provide new insights

University of Rome - Despite moderate HIV viremia, clinical progression risk is low

University of South Florida - siRNA silences Fas expression and inhibits Fas-mediated apoptosis

University of Sydney - Apoptosis of primary neurons is inhibited by varicella-zoster virus ORF63

University of Teheran - Cord blood stem cells clonogenic capacity not impaired by cryopreservation

University of Toronto - After brief cardiac arrest, epinephrine increases mortality in an in vivo rat model

University of Toronto - Tumor angiogenesis flourishes in models with TIMP-3 gene deficiency

University of Turin - Effect of lobectomy on lung function in chronic obstructive pulmonary disease patients examined

University of Wurzburg - Dilated cardiomyopathy pathogenesis and role of beta₁ -adrenergic receptor is reviewed

Uroplasty, Inc. - Uroplasty announces 6-year agreement with French company to distribute incontinence device

VA Research Service, White River Junction - Post-transcriptional signals yield macrophage VEGF

VU University, Amsterdam - Practice of euthanasia related to terminally ill cancer patient's suffering

Vanderbilt University, Nashville - SCN1A-associated epilepsy is linked to a channel dysfunction

Ventracor - Ventracor reports 50th implant of VentrAssist left ventricular assist device

Veterans' Affairs Boston Healthcare System - For cardiovascular disease mortality, systolic BP was most consistent predictor

Wake Forest University, Winston-Salem - Plain radiographs are not required with computed tomography to accurately diagnose blunt trauma

Warsaw University - Melatonin attenuates diabetes-induced oxidative stress in rabbits

Washington State University - Internet-based program increased coping skills in traumatized patients

Washington University, St. Louis - West Nile virus antibodies prevent lethal infection through Fc gamma

WellGen, Inc. - Nutrigenomics-focused biotechnology company completes $3 million series B financing

York University - Resistin exposure regulates skeletal muscle cell insulin signaling, glucose uptake, and metabolism

Zhejiang University - Epithelial ovarian tumors linked to expression and localization of aquaporin-5

Zhejiang University, Zhengzhou - Artificial liver support system safe and effective in acute or chronic liver failure

iCo Therapeutics Inc. - Biotech company selects Isis to manufacture, supply antisense drug for eye diseases

sanofi-aventis - U.S. FDA approves rimonabant for weight management, denies approval for smoking cessation