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Bayr Julius Maximilians University, Germany
Nicotine has genotoxic effects in human cells
July 4th, 2006
Nicotine has genotoxic effects in human cells. "It is accepted that nicotine in tobacco smoke causes addiction via nicotinic acetylcholine receptors in the central nervous system. For a long time, the tumorigenic potential of smoking was attributed to compounds other than nicotine," researchers in Germany report. "However, more recently data have accumulated which suggest that nicotine may add to the cancer risk by stimulating cellular growth via non-neuronal acetylcholine receptors, by suppressing apoptosis, and by inducing angiogenesis not only in atheromatous plaques but also in tumors. In the present study the possible direct genotoxic effects of...
Source: Pharma Law Weekly (2006-07-04)
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