Fraunhofer Institute of Toxicology & Experimental Medicine, Germany
Aspergillus-sensitized early airway response inhibited by a surfactant protein
Published in Pharma Law Weekly, August 22nd, 2006
"The surfactant protein SP-D has been reported to reduce bronchial hyper-responsiveness, blood eosinophilia, and T-helper type 2 cytokines in models of allergic asthma. However, little is known about the functional effect of SP-D on the early airway response upon allergen inhalation, which is an important feature of this disease.
"We investigated whether SP-D is able to reduce the immediate allergen-induced mediator release and the early bronchial obstruction in addition to its effects on airway inflammation...
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Source: Pharma Law Weekly (2006-08-22)
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