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Instituto Portugues de Oncologia, Portugal

Reports from Portugal, Tunisia and the People's Republic of China advance knowledge in nasopharyngeal cancer research

Published in Pharma Law Weekly, September 26th, 2006

Reports from Portugal, Tunisia and the People's Republic of China highlight recent research in nasopharyngeal cancer.

Study 1: Genetic susceptibility to nasopharyngeal carcinoma (NPC) could be linked to the A870G cyclin D1 (CCND1) gene polymorphism.

"NPC is multifactorial, and the genetic background may be a crucial etiologic factor. CCND1 is a key regulator of the cell cycle, and its altered activity is associated with the development of cancer. We analyzed the A870G CCND1 polymorphism by polymerase chain reaction/restriction fragment length polymorphism (PCR-RFLP) in 281 individuals, including 94 patients with NPC and 187 healthy individuals,"...

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