Neurology
Studies from University Hospital in the area of neurology published
Published in Pharma Law Weekly, December 26th, 2006
New investigation results, "Role of drug efflux carriers in the healthy and diseased brain," are detailed in a study published in Annals of Neurology. "The blood-brain barrier is a natural diffusion barrier, which expresses active carriers extruding drugs on their way to the brain back into the blood against concentration gradients. Whereas these so-called adenosine triphosphate-binding cassette (ABC) transporters prevent the brain entry of toxic compounds under physiological conditions, they complicate pharmacotherapies in neurological disease," scientists in Switzerland report.
"Recent observations in animal models of ischemic stroke, drug-resistant epilepsy, and...
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Source: Pharma Law Weekly (2006-12-26)
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