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Studies from University of Aarhus, Department of Pharmacology have provided new information about pharmacology

Published in Pharma Law Weekly, February 20th, 2007

A report, "Elevated pressure selectively blunts flow-evoked vasodilatation in rat mesenteric small arteries," is newly published data in British Journal of Pharmacology. According to recent research from Aarhus, Denmark, "The present study investigated mechanisms underlying impaired endothelium-dependent vasodilatation elicited by elevating the intraluminal pressure in rat mesenteric small arteries. EXPERIMENTAL APPROACH: Arterial segments (internal diameter 316±2 microm, n=86) were mounted in a pressure myograph."

"The effect of elevating pressure from 50 to 120 mmHg for 1 h before resetting it to 50 mmHg was studied on endothelium-dependent vasodilatation. KEY...

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