Gene Therapy

Scientists at Johnson & Johnson report research in gene therapy

Published in Pharma Law Weekly, March 27th, 2007

Fresh data on gene therapy are presented in the report "Human epidermoid A431 cells express functional nicotinic acid receptor HM74a. Nicotinic acid (niacin) has been used clinically to manage dyslipidemia for many years. The molecular target of nicotinic acid was unknown until the recent revelation of human G-coupled receptor HM74a as the high affinity receptor for nicotinic acid," scientists in the United States report.

"In searching for a cell line expressing endogenous human HM74a receptor, we have identified that the A431 cell line, a human epidermoid cell line, expresses a high level of HM74a receptor. An HM74a-specific real time PCR probe set was designed and the...

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Source: Pharma Law Weekly (2007-03-27)

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