Falciparum Malaria Genetics
Study data from All India Institute of Medical Sciences, Department of Biotechnology update understanding of falciparum malaria genetics
Published in Pharma Law Weekly, January 15th, 2008
A new study, 'Extensive genetic diversity in the Plasmodium falciparum Na+/H+ exchanger 1 transporter protein implicated in quinine resistance,' is now available. According to recent research published in the journal Antimicrobial Agents and Chemotherapy, "The Plasmodium falciparum Na(+)/H(+) exchanger (Pfnhe-1) locus at chromosome 13 and another locus at chromosome 9 have recently been proposed to influence quinine resistance. Here, we sequenced the ms4760 locus of the Pfnhe-1 gene from 244 P. falciparum isolates collected from five different regions of India."
"A total of 16 different ms4760 alleles (with one to five DNNND repeats) were observed...
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Source: Pharma Law Weekly (2008-01-15)
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