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Stem Cell Research

Researchers at Henry Ford Hospital, Department of Neurology target stem cell research

Published in Pharma Law Weekly, October 21st, 2008

Current study results from the report, 'Functional response to SDF1 alpha through over-expression of CXCR4 on adult subventricular zone progenitor cells,' have been published. According to a study from the United States, "The chemokine receptor CXCR4 and its ligand, stromal cell derived factor-1 alpha (SDF1 alpha) regulate neuroblast migration towards the ischemic boundary after stroke. Using loss-and gain-function, we investigated the biological effect of CXCR4/SDF1 alpha on neural progenitor cells."

"Neural progenitor cells, from the subventricular zone (SVZ) of the adult rat, were transfected with rat CXCR4-pLEGFP-C1 and pSIREN-RetroQ-CXCR4-siRNA retroviral vectors....

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