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Breast Cancer Therapy

Researchers from Johns Hopkins University, Division of Nuclear Medicine discuss findings in breast cancer therapy

Published in Pharma Law Weekly, October 21st, 2008

Investigators publish new data in the report 'An immunotolerant HER-2/neu transgenic mouse model of metastatic breast cancer.' "Animal models of breast cancer metastases that recapitulate the pattern of metastatic progression seen in patients are lacking; metastatic breast cancer models do not currently exist for evaluation of immune-mediated therapies. We have developed and characterized a preclinical model for the evaluation of immune-mediated metastatic breast cancer therapies," researchers in the United States report.

"The NT2.5 mammary tumor cell line was injected into the left cardiac ventricle of immunotolerant transgenic neu-N mice and athymic nu/nu mice....

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