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Atrophy

Research from J. Simon and co-researchers in the area of atrophy described

Published in Pharma Law Weekly, December 16th, 2008

"To evaluate the efficacy of ultra-low-close 10-microgram 17 beta-estradiol (E2) vaginal tablets for treatment of vaginal atrophy. Postmenopausal women (N=309) were randomly assigned to 10-microgram E2 or placebo vaginal tablets for 52 weeks in a multicenter, double-blind study," scientists writing in the journal Obstetrics and Gynecology report.

"Primary efficacy endpoints included change from baseline to week 12 in vaginal cytology, vaginal pH, and most bothersome urogenital symptoms score. Grading of vaginal health was a secondary efficacy assessment. Safety assessments included endometrial biopsy, physical and gynecologic examinations, and recording adverse...

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