Bioluminescence
Research results from University of Tokyo, Department of Human Genetics update understanding of bioluminescence
Published in Pharma Law Weekly, December 16th, 2008
A new study, 'Establishment of human cell lines showing circadian rhythms of bioluminescence,' is now available. According to recent research from Tokyo, Japan, "We have established human retinal pigment epithelial cell lines stably expressing the luciferase gene, driven by the human Bmal1 promoter, to obtain human-derived cells that show circadian rhythms of bioluminescence after dexamethasone treatment. The average circadian period of bioluminescence for the obtained clones was 24.07±0.48 h."
"Lithium (10 mM) in the medium significantly lengthened the circadian period of bioluminescence, which is consistent with previous reports, while 2 mM or 5 mM lithium had...
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Source: Pharma Law Weekly (2008-12-16)
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