Stem Cell Research

Reports outline stem cell research from INSERM

Published in Pharma Law Weekly, June 2nd, 2009

"The physiological functions of human TCRV gamma 9V delta 2(+) gamma delta lymphocytes reactive to non-peptide phosphoantigens contribute to cancer immunosurveillance and immunotherapy. However, their regulation by mesenchymal stem cells (MSC), multipotent and immunomodulatory progenitor cells able to infiltrate tumors, has not been investigated so far," researchers in Toulouse, France report.

"By analyzing freshly isolated TCRV gamma 9V delta 2(+) lymphocytes and primary cell lines stimulated with synthetic phosphoantigen or B-cell lymphoma cell lines in the presence of MSC, we demonstrated that MSC were potent suppressors of gamma delta-cell proliferation, cytokine...

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Source: Pharma Law Weekly (2009-06-02)

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