Liver Fibrosis

Research findings from L. Luo et al update understanding of liver fibrosis

Published in Pharma Law Weekly, July 14th, 2009

"To investigate the protective effects and the mechanism of anisodamine on deposition of extracellular matrix in experimental liver fibrosis. Experimental liver fibrosis was produced by carbon tetrachloride (CCL4)," scientists in Nantong, People's Republic of China report.

"The preventive group was treated for 10 weeks with anisodamine 7.0 mg/kg per day i.p. injection. Two therapeutic groups were treated for 6 weeks by anisodamine 7.0 or 14.0 mg/kg per day i.p. injection. Studies were made at CCL4 administration on the 10th weekend. Serum biochemical indices and the contents of malondialdehyde (MDA) and hydroxyproline (HYP) in livers were compared. The expression of...

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Source: Pharma Law Weekly (2009-07-14)

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